RT Journal Article
T1 A positive clinical experience of a long-term treatment pattern with leukocyte apheresis and Adacolumn in ulcerative proctitis.
A1 Borrego García, Elena
A1 Peña Ortega, María
A1 Martín-Lagos Maldonado, Alicia
AB Ulcerative proctitis (UP) is often involved in the diagnosis of inflammatory bowel disease (IBD). The increase of leukocytes and pro-inflammatory factors in peripheral blood and in the active forms, as well as the infiltration of neutrophils and monocytes/macrophages in the intestinal mucosa is known to occur in this entity. This infiltration of cells damages the mucosa due to the liberation of proteases, oxidation radicals and cytokines, among others. Apheresis techniques such as leukocyte apheresis may be used among the different therapeutic options such as steroids, sulfasalazine, 5-aminosalicylic, tacrolimus, azathioprine, cyclosporine, mycophenolate and biological agents.
SN 1130-0108
YR 2019
FD 2019
LK https://hdl.handle.net/10668/26072
UL https://hdl.handle.net/10668/26072
LA en
DS RISalud
RD Apr 5, 2025