RT Journal Article
T1 Clinical outcomes of the proximal optimisation technique (POT) in bifurcation stenting.
A1 Chevalier, Bernard
A1 Mamas, Mamas A
A1 Hovasse, Thomas
A1 Rashid, Muhammad
A1 Gómez-Hospital, Joan Antoni
A1 Pan, Manuel
A1 Witkowski, Adam
A1 Crowley, James
A1 Aminian, Adel
A1 McDonald, John
A1 Beygui, Farzin
A1 Fernandez Portales, Javier
A1 Roguin, Ariel
A1 Stankovic, Goran
AB Optimal deployment of coronary stents in a bifurcation lesion remains a matter of debate. We sought to capture the daily practice of bifurcation stenting by means of a worldwide registry and to investigate how post-implantation deployment techniques influence clinical outcomes. Data from the e-ULTIMASTER registry were used to perform an analysis of 4,395 patients undergoing percutaneous coronary intervention for bifurcation lesions. Inverse probability of treatment weights (IPTW) propensity score methodology was used to adjust for any baseline differences. The primary outcome of interest was target lesion failure (TLF) at one year (follow-up rate 96.2%). The global one-year TLF rate was low (5.1%). The proximal optimisation technique (POT) was used in 33.9% of cases and was associated with a reduction in the adjusted TLF rate (4.0% [95% confidence interval: 3.0-5.1%] vs 6.0% [5.1-6.9%], p Despite a low one-year failure rate in this large bifurcation stenting cohort, POT was associated with a further reduction in the event rate and a uniform benefit across subgroups, suggesting systematic use of this deployment technique regardless of the bifurcation anatomy and stenting technique.
YR 2021
FD 2021-12-03
LK https://hdl.handle.net/10668/25644
UL https://hdl.handle.net/10668/25644
LA en
DS RISalud
RD Apr 17, 2025