RT Journal Article T1 An ensemble-based convolutional neural network model powered by a genetic algorithm for melanoma diagnosis A1 Perez, Eduardo A1 Ventura, Sebastian K1 Convolutional neural networks K1 Melanoma diagnosis K1 Ensemble learning K1 Genetic algorithm K1 Lesion segmentation K1 Skin-lesion segmentation K1 Rejective multiple test K1 Deep K1 Classification K1 Images K1 Cnn K1 Tests K1 Big AB Melanoma is one of the main causes of cancer-related deaths. The development of new computational methods as an important tool for assisting doctors can lead to early diagnosis and effectively reduce mortality. In this work, we propose a convolutional neural network architecture for melanoma diagnosis inspired by ensemble learning and genetic algorithms. The architecture is designed by a genetic algorithm that finds optimal members of the ensemble. Additionally, the abstract features of all models are merged and, as a result, additional prediction capabilities are obtained. The diagnosis is achieved by combining all individual predictions. In this manner, the training process is implicitly regularized, showing better convergence, mitigating the overfitting of the model, and improving the generalization performance. The aim is to find the models that best contribute to the ensemble. The proposed approach also leverages data augmentation, transfer learning, and a segmentation algorithm. The segmentation can be performed without training and with a central processing unit, thus avoiding a significant amount of computational power, while maintaining its competitive performance. To evaluate the proposal, an extensive experimental study was conducted on sixteen skin image datasets, where state-of-the-art models were significantly outperformed. This study corroborated that genetic algorithms can be employed to effectively find suitable architectures for the diagnosis of melanoma, achieving in overall 11% and 13% better prediction performances compared to the closest model in dermoscopic and non-dermoscopic images, respectively. Finally, the proposal was implemented in a web application in order to assist dermatologists and it can be consulted at . PB Springer london ltd SN 0941-0643 YR 2021 FD 2021-11-19 LK https://hdl.handle.net/10668/28193 UL https://hdl.handle.net/10668/28193 LA en DS RISalud RD Apr 18, 2025