TY - JOUR AU - Schauer, Stephanie N AU - Carreira, Patricia E AU - Shukla, Ruchi AU - Gerhardt, Daniel J AU - Gerdes, Patricia AU - Sanchez-Luque, Francisco J AU - Nicoli, Paola AU - Kindlova, Michaela AU - Ghisletti, Serena AU - Santos, Alexandre Dos AU - Rapoud, Delphine AU - Samuel, Didier AU - Faivre, Jamila AU - Ewing, Adam D AU - Richardson, Sandra R AU - Faulkner, Geoffrey J PY - 2018 DO - 10.1101/gr.226993.117 UR - http://hdl.handle.net/10668/12334 T2 - Genome research AB - The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human... LA - en KW - ATP Binding Cassette Transporter, Subfamily B KW - Adult KW - Aged KW - Aged, 80 and over KW - Animals KW - Carcinoma, Hepatocellular KW - Cell Transformation, Neoplastic KW - Female KW - Humans KW - Liver KW - Liver Neoplasms KW - Long Interspersed Nucleotide Elements KW - Male KW - Mammals KW - Mice, Knockout KW - Middle Aged KW - Mutagenesis, Insertional KW - Retroelements TI - L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis. TY - research article VL - 28 ER -