RT Journal Article
T1 Kelvin-Voigt Parameters Reconstruction of Cervical Tissue-Mimicking Phantoms Using Torsional Wave Elastography.
A1 Callejas, Antonio
A1 Gomez, Antonio
A1 Faris, Inas H
A1 Melchor, Juan
A1 Rus, Guillermo
K1 Kelvin-Voigt model
K1 Shear Wave Elastography
K1 Torsional Wave Elastography
K1 cervical biomechanics
K1 tissue-mimicking phantom
K1 viscoelasticity
AB The reconstruction of viscous properties of soft tissues, and more specifically, of cervical tissue is a challenging problem. In this paper, a new method is proposed to reconstruct the viscoelastic parameters of cervical tissue-mimicking phantoms by a Torsional Wave Elastography (TWE) technique. The reconstruction method, based on a Probabilistic Inverse Problem (PIP) approach, is presented and experimentally validated against Shear Wave Elastography (SWE). The anatomy of the cervical tissue has been mimicked by means of a two-layer gelatine phantom that simulates the epithelial and connective layers. Five ad hoc oil-in-gelatine phantoms were fabricated at different proportion to test the new reconstruction technique. The PIP approach was used for reconstructing the Kelvin-Voigt (KV) viscoelastic parameters by comparing the measurements obtained from the TWE technique with the synthetic signals from a Finite Difference Time Domain (FDTD) KV wave propagation model. Additionally, SWE tests were realized in order to characterize the viscoelastic properties of each batch of gelatine. Finally, validation was carried out by comparing the KV parameters inferred from the PIP with those reconstructed from the shear wave dispersion curve obtained from the SWE measurements. In order to test the degree of agreement between both techniques, a Student's T-test and a Pearson's correlation study were performed. The results indicate that the proposed method is able to reconstruct the KV viscoelastic properties of the cervical tissue, for both the epithelial and connective layers, as well as the thickness of the first layer with acceptable accuracy.
PB MDPI AG
YR 2019
FD 2019-07-22
LK http://hdl.handle.net/10668/14315
UL http://hdl.handle.net/10668/14315
LA en
NO Callejas A, Gomez A, Faris IH, Melchor J, Rus G. Kelvin-Voigt Parameters Reconstruction of Cervical Tissue-Mimicking Phantoms Using Torsional Wave Elastography. Sensors (Basel). 2019 Jul 25;19(15):3281.
NO This research was supported by the Ministry of Education, DPI2017-83859-R, DPI2014-51870-R, andUNGR15-CE-3664, Ministry of Health DTS15/00093, and Junta de Andalucía PI16/00339, PI-0107-2017, andPIN-0030-2017 projects. Finally, Antonio Callejas is grateful to the Spanish Ministry of Education for the award ofan PhD fellowship.
DS RISalud
RD Apr 6, 2025