RT Journal Article T1 Dual Therapy With Darunavir and Ritonavir Plus Lamivudine vs Triple Therapy With Darunavir and Ritonavir Plus Tenofovir Disoproxil Fumarate and Emtricitabine or Abacavir and Lamivudine for Maintenance of Human Immunodeficiency Virus Type 1 Viral Suppression: Randomized, Open-Label, Noninferiority DUAL-GESIDA 8014-RIS-EST45 Trial A1 Pulido, Federico A1 Ribera, Esteban A1 Lagarde, Maria A1 Perez-Valero, Ignacio A1 Palacios, Rosario A1 Iribarren, Jose A. A1 Payeras, Antoni A1 Domingo, Pere A1 Sanz, Jose A1 Cervero, Miguel A1 Curran, Adrian A1 Rodriguez-Gomez, Francisco J. A1 Tellez, Maria J. A1 Ryan, Pablo A1 Barrufet, Pilar A1 Knobel, Hernando A1 Rivero, Antonio A1 Alejos, Belen A1 Yllescas, Maria A1 Arribas, Jose R. A1 DUAL-GESIDA-8014-RIS-EST45 Study G, K1 darunavir/ritonavir K1 lamivudine K1 switch K1 dual therapy K1 Non-inferiority trial K1 Reverse-transcriptase inhibitor K1 Virologically stable patients K1 Boosted protease inhibitor K1 Antiretroviral therapy K1 Coformulated elvitegravir K1 2 nucleos(t)ides K1 Phase 3b K1 Simplification K1 Hiv AB Background. Our objective was to assess the therapeutic noninferiority of dual therapy with darunavir/ritonavir and lamivudine compared to triple therapy with darunavir/ritonavir plus 2 nucleos(t)ides for maintenance of human immunodeficiency virus type 1 (HIV-1) suppression.Methods. This was a multicenter, open-label, noninferiority trial (margin 12%). Patients with HIV-1 RNA PB Oxford univ press inc SN 1058-4838 YR 2017 FD 2017-12-15 LK http://hdl.handle.net/10668/18942 UL http://hdl.handle.net/10668/18942 LA en DS RISalud RD Apr 12, 2025