RT Journal Article
T1 Quality and Quantity of Protein Intake Influence Incidence of Type 2 Diabetes Mellitus in Coronary Heart Disease Patients: From the CORDIOPREV Study.
A1 de la Cruz-Ares, Silvia
A1 Gutierrez-Mariscal, Francisco M
A1 Alcala-Díaz, Juan F
A1 Quintana-Navarro, Gracia M
A1 Podadera-Herreros, Alicia
A1 Cardelo, Magdalena P
A1 Torres-Peña, Jose D
A1 Arenas-de Larriva, Antonio P
A1 Perez-Martinez, Pablo
A1 Delgado-Lista, Javier
A1 Yubero-Serrano, Elena M
A1 Lopez-Miranda, Jose
K1 Cardiovascular disease
K1 Plant proteins
K1 Type 2 diabetes mellitus
AB Evidence suggests that enriching a diet with plant-based proteins could reduce the risk of developing type 2 diabetes mellitus. In the present work, we evaluated the association between the change in plant protein intake (adjusted by energy) and incidence of type 2 diabetes mellitus in patients with coronary heart disease from the CORDIOPREV (coronary diet intervention with olive oil and cardiovascular prevention) study. At baseline and during the follow-up, patients underwent medical examination and blood and oral glucose tolerance tests. Information on patient's dietary intake was gathered by registered dietitians using a validated food frequency questionnaire. A total of 106 out of 436 nondiabetic patients at baseline developed type 2 diabetes mellitus after a median follow-up of 60 months. Cox regression analyses showed that patients who belonged to the group that increased plant protein intake exhibited a lower risk of developing the disease (HR = 0.64, (0.43-0.96)). Changes in plant protein intake were positively correlated with changes in carbohydrates, fibre, and legumes intake and negatively correlated with changes in saturated fatty acids intake. Results of the present study support the need of improving diet with plant-based proteins to prevent the onset of type 2 diabetes mellitus.
PB MDPI
YR 2021
FD 2021-04-04
LK http://hdl.handle.net/10668/17663
UL http://hdl.handle.net/10668/17663
LA en
NO de la Cruz-Ares S, Gutiérrez-Mariscal FM, Alcalá-Díaz JF, Quintana-Navarro GM, Podadera-Herreros A, Cardelo MP, et al. Quality and Quantity of Protein Intake Influence Incidence of Type 2 Diabetes Mellitus in Coronary Heart Disease Patients: From the CORDIOPREV Study. Nutrients. 2021 Apr 7;13(4):1217
NO We would like to thank the EASP (Escuela Andaluza de Salud Publica), Granada (Spain), for carrying out the randomization process in this study. E.M.Y-S is a recipient of the Nicolás Monardes Programme (C1-0005-2019, Servicio Andaluz de Salud, Junta de Andalucía, Spain). S.C-A. is supported by a Sara Borrell Programme (CD20/00104, Instituto de Salud Carlos III, Spain), A.P.A-L is supported by a Río-Hortega Programme (Instituto de Salud Carlos III). M.P.C. and A.P-H are supported by FIS fellowships (FI17/00081 and FI19/00144, Instituto de Salud Carlos III). F.M.G-M is supported by a research contract from the CIBEROBN. CIBEROBN is an initiative of Instituto deSalud Carlos III, Madrid, Spain.
DS RISalud
RD Apr 12, 2025