RT Journal Article
T1 Grip Strength, Neurocognition, and Social Functioning in People WithType-2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizophrenia
A1 Aliño-Dies, María
A1 Sánchez-Ortí, Joan Vicent
A1 Correa-Ghisays, Patricia
A1 Balanzá-Martínez, Vicent
A1 Vila-Francés, Joan
A1 Selva-Vera, Gabriel
A1 Correa-Estrada, Paulina
A1 Forés-Martos, Jaume
A1 San-Martín Valenzuela, Constanza
A1 Monfort-Pañego, Manuel
A1 Ayesa-Arriola, Rosa
A1 Ruiz-Veguilla, Miguel
A1 Crespo-Facorro, Benedicto
A1 Tabarés-Seisdedos, Rafael
K1 Frailty
K1 Grip strength
K1 Cognitive performance
K1 Social functioning
K1 Severe mental illness
K1 Type-2 diabetes mellitus
K1 Fragilidad
K1 Fuerza de la mano
K1 Interacción social
K1 Trastornos mentales
K1 Diabetes mellitus tipo 2
AB Background: Frailty is a common syndrome among older adults and patients with several comorbidities. Grip strength (GS) is a representative parameter of frailty because it is a valid indicator of current and long-term physical conditions in the general population and patients with severe mental illnesses (SMIs). Physical and cognitive capacities of people with SMIs are usually impaired; however, their relationship with frailty or social functioning have not been studied to date. The current study aimed to determine if GS is a valid predictor of changes in cognitive performance and social functioning in patients with type-2 diabetes mellitus and SMIs. Methods: Assessments of social functioning, cognitive performance, and GS (measured with an electronic dynamometer) were conducted in 30 outpatients with type 2 diabetes mellitus, 35 with major depressive disorder, 42 with bipolar disorder, 30 with schizophrenia, and 28 healthy controls, twice during 1-year, follow-up period. Descriptive analyses were conducted using a one-way analysis of variance for continuous variables and the chi-squared test for categorical variables. Differences between groups for the motor, cognitive, and social variables at T1 and T2 were assessed using a one-way analysis of covariance, with sex and age as co-variates (p < 0.01). To test the predictive capacity of GS at baseline to explain the variance in cognitive performance and social functioning at T2, a linear regression analysis was performed (p < 0.05). Results: Predictive relationships were found among GS when implicated with clinical, cognitive, and social variables. These relationships explained changes in cognitive performance Frontiers in Psychology | www.frontiersin.org 1 November 2020 | Volume 11 | Article 525231 Aliño-Dies et al. Frailty in SMIs and T2DM after one year of follow-up; the variability percentage was 67.7%, in patients with type-2 diabetes mellitus and 89.1% in patients with schizophrenia. Baseline GS along with other variables, also predicted changes in social functioning in major depressive disorder, bipolar disorder, and schizophrenia, with variability percentages of 67.3, 36, and 59%, respectively. Conclusion: GS combined with other variables significantly predicted changes in cognitive performance and social functioning in people with SMIs or type-2 diabetes mellitus. Interventions aimed to improve the overall physical conditions of patients who have poor GS could be a therapeutic option that confers positive effects on cognitive performance and social functioning.
PB Frontiers
YR 2020
FD 2020-11-25
LK http://hdl.handle.net/10668/4004
UL http://hdl.handle.net/10668/4004
LA en
NO Aliño-Dies M, Sánchez-Ortí JV, Correa-Ghisays P, Balanzá-Martínez V, Vila-Francés J, Selva-Vera G, et al. Grip Strength, Neurocognition, and Social Functioning in People WithType-2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizophrenia. Front Psychol. 2020 Nov 25;11:525231
DS RISalud
RD Apr 6, 2025