TY  - JOUR
AU  - García-Calderón, Clara B
AU  - Bejarano-García, José Antonio
AU  - Tinoco-Gago, Isabel
AU  - Castro, María José
AU  - Moreno-Gordillo, Paula
AU  - Piruat, José I
AU  - Caballero-Velázquez, Teresa
AU  - Pérez-Simón, José A
AU  - Rosado, Iván V
PY  - 2018
DO  - 10.1038/s41418-018-0089-4
UR  - http://hdl.handle.net/10668/12214
T2  - Cell death and differentiation
AB  - Metabolically reactive formaldehyde is a genotoxin and a carcinogen. Mice lacking the main formaldehyde-detoxifying gene Adh5 combined with the loss of the Fanconi anemia (FA) DNA repair pathway rapidly succumbed to bone marrow failure (BMF) primarily...
LA  - en
KW  - Alcohol Dehydrogenase
KW  - Animals
KW  - Apoptosis
KW  - Cell Line
KW  - Chickens
KW  - DNA Damage
KW  - DNA Repair
KW  - Fanconi Anemia Complementation Group Proteins
KW  - Genomic Instability
KW  - Hematopoiesis
KW  - Hematopoietic Stem Cells
KW  - Histones
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Phosphorylation
KW  - Tetrahydrofolates
KW  - Thymidylate Synthase
TI  - Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells.
TY  - research article
VL  - 25
ER  -