TY - JOUR AU - Gavish-Izakson, Michal AU - Velpula, Bhagya Bhavana AU - Elkon, Ran AU - Prados-Carvajal, Rosario AU - Barnabas, Georgina D AU - Ugalde, Alejandro Pineiro AU - Agami, Reuven AU - Geiger, Tamar AU - Huertas, Pablo AU - Ziv, Yael AU - Shiloh, Yosef PY - 2018 DO - 10.1093/nar/gkx1240 UR - http://hdl.handle.net/10668/11921 T2 - Nucleic acids research AB - The DNA damage response (DDR) is an extensive signaling network that is robustly mobilized by DNA double-strand breaks (DSBs). The primary transducer of the DSB response is the protein kinase, ataxia-telangiectasia, mutated (ATM). Here, we establish... LA - en KW - Ataxia Telangiectasia Mutated Proteins KW - Cell Line, Tumor KW - DNA KW - DNA Breaks, Double-Stranded KW - DNA Repair KW - G2 Phase Cell Cycle Checkpoints KW - HeLa Cells KW - Humans KW - Nuclear Proteins KW - Phosphorylation KW - Poly(A)-Binding Protein I KW - Protein Binding KW - Protein Interaction Maps KW - RNA Interference TI - Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair. TY - research article VL - 46 ER -