RT Journal Article
T1 Distribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain.
A1 van der Meer, Thomas P
A1 Artacho-Cordón, Francisco
A1 Swaab, Dick F
A1 Struik, Dicky
A1 Makris, Konstantinos C
A1 Wolffenbuttel, Bruce H R
A1 Frederiksen, Hanne
A1 van Vliet-Ostaptchouk, Jana V
K1 bisphenol-A
K1 brain
K1 hypothalamus
K1 methylparaben
K1 obesity
K1 parabens
K1 phenols
AB Non-persistent endocrine disrupting chemicals (npEDCs) can affect multiple organs and systems in the body. Whether npEDCs can accumulate in the human brain is largely unknown. The major aim of this pilot study was to examine the presence of environmental phenols and parabens in two distinct brain regions: the hypothalamus and white-matter tissue. In addition, a potential association between these npEDCs concentrations and obesity was investigated. Post-mortem brain material was obtained from 24 individuals, made up of 12 obese and 12 normal-weight subjects (defined as body mass index (BMI) > 30 and BMI  30 and BMI
YR 2017
FD 2017-09-13
LK http://hdl.handle.net/10668/11577
UL http://hdl.handle.net/10668/11577
LA en
DS RISalud
RD Apr 4, 2025