TY - JOUR AU - Blanco-Ruiz, Marina AU - Amaya-Pascasio, Laura AU - de Torres Chacon, Reyes AU - Josefa Alvarez Soria, Maria AU - Arjona-Padillo, Antonio AU - Carrillo Bailen, Maria Magdalena AU - Milan Pinilla, Rodrigo AU - Perez Ortega, Irene AU - Sanchez Rodriguez, Belen AU - Andrade Zumarraga, Luis AU - Valverde Moyano, Roberto AU - Payan Ortiz, Manuel AU - Castillo Fernandez, Alba Maria AU - Del Toro Perez, Cristina AU - Gonzalez Bustos, Pablo AU - Aguera Morales, Eduardo AU - Sanchez Lopez, Purificacion AU - Hidalgo Martin, Beatriz AU - Roa Chamorro, Ricardo AU - Fernandez Perez, Javier AU - Mejias Olmedo, Maria Victoria AU - Martinez-Sanchez, Patricia PY - 2021 DO - 10.1016/j.athplu.2021.08.009 UR - https://hdl.handle.net/10668/24985 T2 - Atherosclerosis plus AB - Background and aims: The benefits of the PCSK9 inhibitors, alirocumab and evolocumab, in lowering LDL-cholesterol and preventing major adverse cardiac events (MACE) have been demonstrated in pivotal clinical trials. However, few studies of routine... LA - en PB - Elsevier KW - Evolocumab KW - Alirocumab KW - PCSK9i KW - Hypercholesterolemia familiar KW - Cardiovascular disease KW - Statins intolerance KW - Heterozygous familial hypercholesterolemia KW - Statin therapy KW - Double-blind KW - Evolocumab KW - Management KW - Ezetimibe KW - Trial TI - Effectiveness and safety of PCSK9 inhibitors in real-world clinical practice. An observational multicentre study. The IRIS-PCSK9I study TY - research article VL - 45 ER -