TY - JOUR AU - Beeh, Kai M AU - Burgel, Pierre-Regis AU - Franssen, Frits M E AU - Lopez-Campos, Jose Luis AU - Loukides, Stelios AU - Hurst, John R AU - Fležar, Matjaž AU - Ulrik, Charlotte Suppli AU - Di Marco, Fabiano AU - Stolz, Daiana AU - Valipour, Arschang AU - Casserly, Brian AU - Ställberg, Björn AU - Kostikas, Konstantinos AU - Wedzicha, Jadwiga A PY - 2017 DO - 10.1164/rccm.201609-1794CI UR - http://hdl.handle.net/10668/10662 T2 - American journal of respiratory and critical care medicine AB - Decreasing the frequency and severity of exacerbations is one of the main goals of treatment for patients with chronic obstructive pulmonary disease. Several studies have documented that long-acting bronchodilators can reduce exacerbation rate and/or... LA - en KW - hyperinflation KW - inflammation KW - inhaled corticosteroid KW - mucus KW - Administration, Inhalation KW - Adrenergic beta-2 Receptor Agonists KW - Bronchodilator Agents KW - Drug Therapy, Combination KW - Humans KW - Muscarinic Antagonists KW - Pulmonary Disease, Chronic Obstructive TI - How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease? TY - research article VL - 196 ER -