RT Journal Article
T1 Satisfaction with oral anticoagulants in patients with atrial fibrillation.
A1 Suárez Fernández, Carmen
A1 Castilla-Guerra, Luis
A1 Cantero Hinojosa, Jesus
A1 Suriñach, Josep Maria
A1 Acosta de Bilbao, Fernando
A1 Tamarit, Juan José
A1 Diaz Diaz, José Luis
A1 Hernandez, Jose Luis
A1 Pose, Antonio
A1 Montero-Pérez-Barquero, Manuel
A1 Roquer, Jaume
A1 Gállego, Jaime
A1 Vivancos, José
A1 Mostaza, Jose María
K1 atrial fibrillation
K1 benefit
K1 burdens
K1 direct oral anticoagulants
K1 satisfaction
K1 vitamin K antagonists
AB Although, by itself, atrial fibrillation is associated with an impairment of quality of life antithrombotic therapy may play a role. To evaluate the satisfaction with anticoagulant treatment in patients with nonvalvular atrial fibrillation who attended internal medicine departments in Spain. Patients from two different cross-sectional studies were combined. To measure the satisfaction with anticoagulant treatment, the Anti-Clot-Treatment Scale (ACTS) questionnaire was completed by every patient. A multivariate analysis was performed to determine the variables associated with satisfaction of patients receiving oral anticoagulants. A total of 1,309 patients (mean age 78.5±8.4 years; 49.3% men; CHA2DS2VASC 4.9±1.5; HAS-BLED 2.0±0.9) were included in the study, of whom 902 (68.9%) were taking vitamin K antagonists (VKA) and 407 (31.1%) direct oral anticoagulants (DOACs). Overall, satisfaction with oral anticoagulation was high (ACTS Burdens scale 49.69±9.45; ACTS Benefits scale 11.35±2.61). The perceived burdens with anticoagulant treatment were lower in men, as well as in patients with no dependency, normal renal function, who were not polymedicated, or who had moderate bleeding risk. Among patients taking VKA, those subjects with a lower number of International Normalized Ratio (INR) determinations in the last 6 months or with an optimal time in the therapeutic range exhibited a lower perceived burden. Patients taking DOACs (vs VKA) showed a lower perceived burden with anticoagulation. Benefits with anti-coagulation were higher in men, younger patients, those with no dependency, or low bleeding risk. Perceived benefits were higher in patients taking DOACs (vs VKA). Satisfaction with oral anticoagulation was high in patients with nonvalvular atrial fibrillation, who were attending internal medicine departments daily in Spain. Among patients taking VKA, those subjects with a lower number of INR determinations in the last 6 months or with an optimal time in the therapeutic range exhibited a lower perceived burden with anticoagulant therapy. Patients taking DOACs (vs VKA) showed lower perceived burdens and higher perceived benefits with anticoagulation.
SN 1177-889X
YR 2018
FD 2018-02-19
LK https://hdl.handle.net/10668/26237
UL https://hdl.handle.net/10668/26237
LA en
DS RISalud
RD Apr 6, 2025