RT Journal Article T1 Microstructural and Strength Changes in Trabecular Bone in Elderly Patients with Type 2 Diabetes Mellitus. A1 Giner, Mercè A1 Miranda, Cristina A1 Vázquez-Gámez, María Angeles A1 Altea-Manzano, Patricia A1 Miranda, María-José A1 Casado-Díaz, Antonio A1 Pérez-Cano, Ramón A1 Montoya-García, María-José K1 diagnostic K1 fracture K1 hip K1 imaging K1 osteoporosis K1 trauma K1 type 2 diabetes mellitus AB Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide and it is associated with an increased risk of osteoporosis and fragility fractures. Our aim is to analyze the effect of T2DM on bone quality. This is a case-control study. The studied population consisted of 140 patients: 54 subjects with hip fracture (OP) without T2DM, 36 patients with hip fracture and T2DM (OP-T2DM), 28 patients with osteoarthritis (OA) without T2DM, and 22 patients with OA and T2DM (OA-T2DM). Bone markers, bone mineral density, FRAX score, microstructural, and bone material strength from femoral heads were assessed. The group with hip fracture presented lower BMD values than OA (p SN 2075-4418 YR 2021 FD 2021-03-23 LK https://hdl.handle.net/10668/25953 UL https://hdl.handle.net/10668/25953 LA en DS RISalud RD Apr 17, 2025