RT Journal Article
T1 Multidisciplinary Unit Improves Pregnancy Outcomes in Women with Rheumatic Diseases and Hereditary Thrombophilias: An Observational Study.
A1 Añón-Oñate, Isabel
A1 Cáliz-Cáliz, Rafael
A1 Rosa-Garrido, Carmen
A1 Pérez-Galán, María José
A1 Quirosa-Flores, Susana
A1 Pancorbo-Hidalgo, Pedro L
K1 antiphospholipid syndrome
K1 foetal death
K1 hereditary thrombophilias
K1 miscarriage
K1 multidisciplinary consultation
K1 pregnancy
K1 rheumatic diseases
K1 systemic lupus erythematosus
AB Rheumatic diseases (RD) and hereditary thrombophilias (HT) can be associated with high-risk pregnancies. This study describes obstetric outcomes after receiving medical care at a multidisciplinary consultation (MC) and compares adverse neonatal outcomes (ANOs) before and after medical care at an MC. This study is a retrospective observational study among pregnant women with RD and HT treated at an MC of a university hospital (southern Spain) from 2012 to 2018. Absolute risk reduction (ARR) and number needed to treat (NNT) were calculated. A total of 198 pregnancies were registered in 143 women (112 with RD, 31 with HT), with 191 (96.5%) pregnancies without ANOs and seven (3.5%) pregnancies with some ANOs (five miscarriages and two foetal deaths). Results previous to the MC showed 60.8% of women had more than one miscarriage, with 4.2% experiencing foetal death. MC reduced the ANO rate by AAR = 60.1% (95%CI: 51.6-68.7%). The NNT to avoid one miscarriage was 1.74 (95%CI: 1.5-2.1) and to avoid one foetal death NNT = 35.75 (95CI%: 15.2-90.9). A total of 84.8% of newborns and 93.2% of women did not experience any complication. As a conclusion, the follow-up of RD or HT pregnant women in the MC drastically reduced the risk of ANOs in this population with a previous high risk.
SN 2077-0383
YR 2021
FD 2021-04-03
LK http://hdl.handle.net/10668/17661
UL http://hdl.handle.net/10668/17661
LA en
DS RISalud
RD Apr 19, 2025