RT Journal Article
T1 Use of Infrared Thermography to Estimate Brown Fat Activation After a Cooling Protocol in Patients with Severe Obesity That Underwent Bariatric Surgery.
A1 Piquer-Garcia, Irene
A1 Cereijo, Ruben
A1 Corral-Perez, Juan
A1 Pellitero, Silvia
A1 Martinez, Eva
A1 Taxeras, Siri D
A1 Tarasco, Jordi
A1 Moreno, Pau
A1 Balibrea, Jose
A1 Puig-Domingo, Manel
A1 Serra, Dolors
A1 Herrero, Laura
A1 Jimenez-Pavon, David
A1 Lerin, Carles
A1 Villarroya, Francesc
A1 Sanchez-Infantes, David
K1 Brown adipose tissue
K1 Infrared thermography
K1 Metabolic surgery
K1 Obesity
AB In contrast to the energy-storing role of white adipose tissue (WAT), brown adipose tissue (BAT) acts as the main site of non-shivering thermogenesis in mammals and has been reported to play a role in protection against obesity and associated metabolic alterations in rodents. Infrared thermography (IRT) has been proposed as a novel non-invasive, safe, and quick method to estimate BAT thermogenic activation in humans. The aim of this study is to determine whether the IRT could be a potential new tool to estimate BAT thermogenic activation in patients with severe obesity in response to bariatric surgery. Supraclavicular BAT thermogenic activation was evaluated using IRT in a cohort of 31 patients (50 ± 10 years old, BMI = 44.5 ± 7.8; 15 undergoing laparoscopy sleeve gastrectomy and 16 Roux-en-Y gastric bypass) at baseline and 6 months after a bariatric surgery. Clinical parameters were determined at these same time points. Supraclavicular BAT-related activity was detected in our patients by IRT after a cooling stimulus. The BAT thermogenic activation was higher at 6 months after laparoscopy sleeve gastrectomy (0.06 ± 0.1 vs 0.32 ± 0.1), while patients undergoing to a roux-en-Y gastric bypass did not change their thermogenic response using the same cooling stimulus (0.09 ± 0.1 vs 0.08 ± 0.1). Our study postulates the IRT as a potential tool to evaluate BAT thermogenic activation in patients with obesity before and after a bariatric surgery. Further studies are needed to evaluate differences between LSG technique and RYGB on BAT activation.
PB Springer New York LLC
YR 2020
FD 2020-03-04
LK http://hdl.handle.net/10668/15204
UL http://hdl.handle.net/10668/15204
LA en
NO Piquer-Garcia I, Cereijo R, Corral-Pérez J, Pellitero S, Martínez E, Taxerås SD, et al. Use of Infrared Thermography to Estimate Brown Fat Activation After a Cooling Protocol in Patients with Severe Obesity That Underwent Bariatric Surgery. Obes Surg. 2020 Jun;30(6):2375-2381
NO Samples from patients included in this study were provided by the IGTP HUGTP Biobank integrated in the Spanish National Biobanks Network of “Instituto de Salud Carlos III”(PT13/0010/0009), and they were processed following standard operating procedures with the appropriate approval of the Ethical and ScientificCommittees.
DS RISalud
RD Apr 12, 2025