RT Journal Article
T1 Mediterranean Diet and Endothelial Function: A Review of its Effects at Different Vascular Bed Levels
A1 Torres-Peña, Jose D.
A1 Rangel-Zuñiga, Oriol A.
A1 Alcala-Diaz, Juan F.
A1 Lopez-Miranda, Jose
A1 Delgado-Lista, Javier
K1 Endothelial function
K1 Cardiovascular disease
K1 Mediterranean diet
K1 Células endoteliales
K1 Enfermedades cardiovasculares
K1 Dieta mediterránea
AB The Mediterranean diet has recently been the focus of considerable attention as a palatable model of a healthy diet. Its influence on many cardiovascular risk factors, combined with its proven effect in reducing the risk of cardiovascular events in primary prevention, has boosted scientific interest in this age-old nutritional model. Many of the underlying mechanisms behind its health-giving effects have been revealed, from the modulation of the microbiota to the function of high-density lipoproteins (HDL), and it seems to deliver its health benefits mainly by regulating several key mechanisms of atherosclerosis. In this review, we will review the evidence for its regulation of endothelial function, a key element in the early and late stages of atherosclerosis. In addition, we will assess studies which evaluate its effects on the functioning of different arterial territory vessels (mainly the microvascular, peripheral and central vascular beds), focusing mainly on the capillary, brachial and carotid arteries. Finally, we will evaluate the molecular mechanisms which may be involved.
PB MDPI
YR 2020
FD 2020-07-24
LK http://hdl.handle.net/10668/3854
UL http://hdl.handle.net/10668/3854
LA en
NO Torres-Peña JD, Rangel-Zuñiga OA, Alcala-Diaz JF, Lopez-Miranda J, Delgado-Lista J. Mediterranean Diet and Endothelial Function: A Review of its Effects at Different Vascular Bed Levels. Nutrients. 2020 Jul 24;12(8):2212
DS RISalud
RD Aug 1, 2025