RT Journal Article
T1 Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group
A1 Franco Pérez, Fernando
A1 Lavernia, Javier
A1 Aguiar-Bujanda, David
A1 Miramón, José
A1 Gumá, Josep
A1 Álvarez, Rut
A1 Gómez-Codina, José
A1 García Arroyo, Francisco
A1 Llanos, Marta
A1 Marin, Miguel
A1 Alfaro, Jesus
A1 Quero, Cristina
A1 Delgado, Mayte
A1 Nogales, Esteban
A1 Menarguez, Francisco
A1 Martinez, Natividad
A1 Torrente, Maria
A1 Royuela, Ana
A1 Abreu, Delvys
A1 Provencio, Mariano
K1 Chemotherapy
K1 Extranodal lymphoma
K1 Immunotherapy
K1 Lumpectomy
K1 Neoplasms of the breast
K1 Neoplasias de la mama
K1 Consenso
K1 Supervivencia sin rnfermedad
K1 Inmunoterapia
K1 Incidencia
K1 Ganglios linfáticos
K1 Linfoma
K1 Linfoma no hodgkin
K1 Glándulas mamarias humanas
AB NTRODUCTION:Primary breast lymphoma is a rare form of localized extranodal lymphoma, which affects the mammary glands unilaterally or bilaterally, and can also affect the regional lymph nodes.MATERIALS AND METHODS:We reviewed 55 patients, with disease stages IE and IIE, diagnosed in 16 Spanish institutions between 1989 and 2016. A serial of clinical variables and treatment were collected, and overall survival (OS) and progression-free survival (PFS) were calculated.RESULTS:Of the 55 patients, 96.4% were women with an average age of 69 years. A total of 53 patients corresponded to non-Hodgkin lymphoma (NHL), of whom 36.3% had lymph node involvement upon diagnosis. Of the patients, 58.2% were stage IE, and 41.8% were stage IIE. Treatments received included radiotherapy (36.3%), chemotherapy (85.5%), and rituximab (in 38 of the 45 patients with NHL treated with chemotherapy). In all, 82.2% of complete responses were achieved. OS and progression-free survival at 5 years in NHL patients was 76% and 73%, respectively.CONCLUSION:Current treatments (chemotherapy, immunotherapy, and radiotherapy) achieve good control of the disease, with an OS of 5 years in 80% of the patients, although there is no consensus in treatment, given the scarce incidence of these lymphomas.
PB Elsevier
SN 2152-2650
YR 2017
FD 2017-03
LK http://hdl.handle.net/10668/2641
UL http://hdl.handle.net/10668/2641
LA en
NO Franco Pérez F, Lavernia J, Aguiar-Bujanda D, Miramón J, Gumá J, Álvarez R et al. Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group.Clin Lymphoma Myeloma Leuk. 2017 Mar;17(3):186-191.
DS RISalud
RD Apr 5, 2025