%0 Journal Article
%A Franco Pérez, Fernando
%A Lavernia, Javier
%A Aguiar-Bujanda, David
%A Miramón, José
%A Gumá, Josep
%A Álvarez, Rut
%A Gómez-Codina, José
%A García Arroyo, Francisco
%A Llanos, Marta
%A Marin, Miguel
%A Alfaro, Jesus
%A Quero, Cristina
%A Delgado, Mayte
%A Nogales, Esteban
%A Menarguez, Francisco
%A Martinez, Natividad
%A Torrente, Maria
%A Royuela, Ana
%A Abreu, Delvys
%A Provencio, Mariano
%T Primary Breast Lymphoma: Analysis of 55 Cases of the Spanish Lymphoma Oncology Group
%D 2017
%@ 2152-2650
%U http://hdl.handle.net/10668/2641
%X NTRODUCTION:Primary breast lymphoma is a rare form of localized extranodal lymphoma, which affects the mammary glands unilaterally or bilaterally, and can also affect the regional lymph nodes.MATERIALS AND METHODS:We reviewed 55 patients, with disease stages IE and IIE, diagnosed in 16 Spanish institutions between 1989 and 2016. A serial of clinical variables and treatment were collected, and overall survival (OS) and progression-free survival (PFS) were calculated.RESULTS:Of the 55 patients, 96.4% were women with an average age of 69 years. A total of 53 patients corresponded to non-Hodgkin lymphoma (NHL), of whom 36.3% had lymph node involvement upon diagnosis. Of the patients, 58.2% were stage IE, and 41.8% were stage IIE. Treatments received included radiotherapy (36.3%), chemotherapy (85.5%), and rituximab (in 38 of the 45 patients with NHL treated with chemotherapy). In all, 82.2% of complete responses were achieved. OS and progression-free survival at 5 years in NHL patients was 76% and 73%, respectively.CONCLUSION:Current treatments (chemotherapy, immunotherapy, and radiotherapy) achieve good control of the disease, with an OS of 5 years in 80% of the patients, although there is no consensus in treatment, given the scarce incidence of these lymphomas.
%K Chemotherapy
%K Extranodal lymphoma
%K Immunotherapy
%K Lumpectomy
%K Neoplasms of the breast
%K Neoplasias de la mama
%K Consenso
%K Supervivencia sin rnfermedad
%K Inmunoterapia
%K Incidencia
%K Ganglios linfáticos
%K Linfoma
%K Linfoma no hodgkin
%K Glándulas mamarias humanas
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