RT Journal Article
T1 Targeting body composition in an older population: do changes in movement behaviours matter? Longitudinal analyses in the PREDIMED-Plus trial.
A1 Galmes-Panades, Aina M
A1 Konieczna, Jadwiga
A1 Varela-Mato, Veronica
A1 Abete, Itziar
A1 Babio, Nancy
A1 Fiol, Miquel
A1 Antonio de Paz, José
A1 Casas, Rosa
A1 Olbeyra, Romina
A1 Ruiz-Canela, Miguel
A1 Palau-Galindo, Antoni
A1 Castañer, Olga
A1 Martín-García, Arturo
A1 Estruch, Ramón
A1 Vidal, Josep
A1 Buil-Cosiales, Pilar
A1 Wärnberg, Julia
A1 Salas-Salvadó, Jordi
A1 Martínez, J Alfredo
A1 Romaguera, Dora
A1 PREDIMED-Plus investigators, 
K1 Body composition
K1 Isotemporal substitution
K1 Physical activity
K1 Sedentary behaviour
K1 Visceral adipose tissue
AB The optimal distribution between physical activity (PA) levels and sedentary behaviour (SB) for the greatest benefits for body composition among older adults with overweight/obesity and chronic health conditions remains unclear. We aimed to determine the prospective association between changes in PA and in SB with concurrent changes in body composition and to examine whether reallocating inactive time into different physical activity levels was associated with 12-month change to body composition in older adults. Longitudinal assessment nested in the PREDIMED-Plus trial. A subsample (n = 1564) of men and women (age 55-75 years) with overweight/obesity and metabolic syndrome from both arms of the PREDIMED-Plus trial was included in the present analysis. Participants were followed up at 6 and 12 months. Physical activity and SB were assessed using validated questionnaires. Out of 1564 participants, 388 wore an accelerometer to objectively measure inactive time and PA over a 7-day period. At each time point, participants' body composition was measured using dual-energy X-ray absorptiometry (DXA). Standard covariate-adjusted and isotemporal substitution modelling were applied to linear mixed-effects models. Increasing 30 min of total PA and moderate-to-vigorous physical activity (MVPA) was associated with significant reductions in body fat (β - 0.07% and - 0.08%) and visceral adipose tissue (VAT) (- 13.9 g, and - 15.6 g) at 12 months (all p values  At 12 months, increasing total PA and MVPA and reducing total SB and TV-viewing SB were associated with improved body composition in participants with overweight or obesity, and metabolic syndrome. This was also observed when substituting 30 min of inactive time with total PA, LPA and MVPA, with the greatest benefits observed with MVPA. International Standard Randomized Controlled Trial (ISRCTN), 89898870 . Retrospectively registered on 24 July 2014.
YR 2021
FD 2021-01-06
LK http://hdl.handle.net/10668/16928
UL http://hdl.handle.net/10668/16928
LA en
DS RISalud
RD Apr 11, 2025