TY - JOUR AU - Boughanem, Hatim AU - Cabrera-Mulero, Amanda AU - Hernandez-Alonso, Pablo AU - Clemente-Postigo, Mercedes AU - Casanueva, Felipe F AU - Tinahones, Francisco J AU - Morcillo, Sonsoles AU - Crujeiras, Ana B AU - Macias-Gonzalez, Manuel PY - 2020 DO - 10.1186/s13148-020-00875-9 UR - http://hdl.handle.net/10668/15712 T2 - Clinical epigenetics AB - Colorectal cancer (CRC) results from the accumulation of epigenetic and genetic changes in colon cells during neoplasic transformation, which the activation of Wingless (Wnt) signaling pathway is a common mechanism for CRC initiation. The Wnt pathway... LA - en PB - BioMed Central KW - 25-OH vitamin D KW - Colorectal cancer KW - Neoadjuvant treatment KW - SFRP2 methylation KW - Aged KW - Colorectal neoplasms KW - DNA methylation KW - Epigenomics KW - Female KW - HCT116 cells KW - Humans KW - Intra-abdominal fat KW - Leukocytes, mononuclear KW - Linear models KW - Male KW - Membrane proteins KW - Middle aged KW - Neoadjuvant therapy KW - Promoter regions, genetic KW - Vitamin D KW - Wnt signaling pathway TI - Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer. TY - research article VL - 12 ER -