TY - JOUR AU - Oliver, Jaime Antonio AU - Ortiz, Raúl AU - Melguizo, Consolación AU - Álvarez, Pablo Juan AU - Gómez-Millán, Jaime AU - Prados, José PY - 2014 DO - 10.1186/1471-2407-14-511 UR - http://hdl.handle.net/10668/1807 T2 - BMC cancer AB - BACKGROUNDNew biomarkers are needed for the prognosis of advanced colorectal cancer, which remains incurable by conventional treatments. O6-methylguanine DNA methyltransferase (MGMT) methylation and protein expression have been related to colorectal... LA - en PB - BioMed Central KW - Colorectal cancer KW - MGMT KW - CD133 KW - Methylation status KW - Biomarker KW - Overall survival KW - Disease free-survival KW - Neoplasias colorrectales KW - Marcadores biológicos de tumor KW - Metilación de ADN KW - Pronóstico KW - Regiones promotoras genéticas KW - Supervivencia sin enfermedad KW - Enzimas reparadoras del ADN KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Tumor Markers, Biological KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid::Promoter Regions, Genetic KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::DNA Repair Enzymes KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans TI - Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma. TY - research article ER -