TY - JOUR AU - Mayoral-Gonzalez, Isabel AU - Calderon-Sanchez, Eva M AU - Galeano-Otero, Isabel AU - Martin-Bornez, Marta AU - Gutierrez-Carretero, Encarnacion AU - Fernandez-Velasco, Maria AU - Domenech, Nieves AU - Crespo-Leiro, Maria Generosa AU - Gomez, Ana Maria AU - OrdoƱez-Fernandez, Antonio AU - Hmadcha, Abdelkrim AU - Smani, Tarik PY - 2022 DO - 10.1016/j.omtn.2022.01.003 SN - 2162-2531 UR - http://hdl.handle.net/10668/22458 T2 - Molecular therapy. Nucleic acids AB - Urocortin-2 (Ucn-2) has demonstrated cardioprotective actions against myocardial ischemia-reperfusion (I/R) injuries. Herein, we explored the protective role of Ucn-2 through microRNAs (miRNAs) post-transcriptional regulation of apoptotic and... LA - en PB - Cell Press KW - Ucn-2 KW - apoptosis KW - cardiac remodeling KW - fibrosis KW - heart failure KW - ischemia and reperfusion KW - miRNA KW - MicroRNAs KW - Myocardial Reperfusion Injury KW - Urocortins KW - Up-Regulation KW - L-Lactate Dehydrogenase KW - Myocytes, Cardiac KW - Fibrosis KW - Reperfusion TI - Cardiac protection induced by urocortin-2 enables the regulation of apoptosis and fibrosis after ischemia and reperfusion involving miR-29a modulation. TY - research article VL - 27 ER -