TY - JOUR AU - Leon, Silvia AU - Barroso, Alexia AU - Vazquez, Maria J AU - Garcia-Galiano, David AU - Manfredi-Lozano, Maria AU - Ruiz-Pino, Francisco AU - Heras, Violeta AU - Romero-Ruiz, Antonio AU - Roa, Juan AU - Schutz, Günther AU - Kirilov, Milen AU - Gaytan, Francisco AU - Pinilla, Leonor AU - Tena-Sempere, Manuel PY - 2015 DO - 10.1038/srep19206 UR - http://hdl.handle.net/10668/9725 T2 - Scientific reports AB - Kisspeptins, ligands of the receptor, Gpr54, are potent stimulators of puberty and fertility. Yet, whether direct kisspeptin actions on GnRH neurons are sufficient for the whole repertoire of their reproductive effects remains debatable. To dissect... LA - en PB - Nature Publishing Group KW - Animals KW - Feedback, physiological KW - Female KW - Fertility KW - Gonadotropin-releasing hormone KW - Gonadotropins KW - Kisspeptins KW - Male KW - Mice KW - Mice, knockout KW - Neurons KW - Ovary KW - Phenotype KW - Receptors, G-protein-coupled KW - Receptors, kisspeptin-1 KW - Reproduction KW - Testis TI - Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity. TY - Research article VL - 6 ER -