RT Journal Article
T1 An exploratory, large-scale study of pain and quality of life outcomes in cancer patients with moderate or severe pain, and variables predicting improvement.
A1 Maximiano, Constanza
A1 Lopez, Iker
A1 Martin, Cristina
A1 Zugazabeitia, Luis
A1 Marti-Ciriquian, Juan L
A1 Nuñez, Miguel A
A1 Contreras, Jorge
A1 Herdman, Michael
A1 Traseira, Susana
A1 Provencio, Mariano
K1 Neoplasms
K1 Pain Management
K1 Pain Measurement
K1 Quality of Life
AB There have been few large-scale, real world studies in Spain to assess change in pain and quality of life (QOL) outcomes in cancer patients with moderate to severe pain. This study aimed to assess changes on both outcomes after 3 months of usual care and to investigate factors associated with change in QoL. Large, multi-centre, observational study in patients with lung, head and neck, colorectal or breast cancer experiencing a first episode of moderate to severe pain while attending one of the participating centres. QoL was assessed using the EuroQol-5D questionnaire and pain using the Brief Pain Inventory (BPI). Instruments were administered at baseline and after 3 months of follow up. Multivariate analyses were used to assess the impact of treatment factors, demographic and clinical variables, pain and other symptoms on QoL scores. 1711 patients were included for analysis. After 3 months of usual care, a significant improvement was observed in pain and QoL in all four cancer groups (p In the four cancer types studied, pain and QoL outcomes improved considerably after 3 months of usual care. Improvements in pain made a substantial contribution to QoL gains whilst the presence of anxiety and depression and poor baseline performance status significantly constrained improvement.
PB Public Library of Science
YR 2018
FD 2018-04-03
LK http://hdl.handle.net/10668/12303
UL http://hdl.handle.net/10668/12303
LA en
NO Maximiano C, López I, Martín C, Zugazabeitia L, Martí-Ciriquián JL, Núñez MA, et al. An exploratory, large-scale study of pain and quality of life outcomes in cancer patients with moderate or severe pain, and variables predicting improvement. PLoS One. 2018 Apr 3;13(4):e0193233
DS RISalud
RD Apr 9, 2025