TY - JOUR AU - Cavalcanti, Fernando AU - Gonzalez-Rey, Elena AU - Delgado, Mario AU - Falo, Clara P AU - Mestre, Leyre AU - Guaza, Carmen AU - O'Valle, Francisco AU - Lufino, Michele M P AU - Xaus, Jordi AU - MascarĂ³, Cristina AU - Lunardi, Serena AU - Sacilotto, Natalia AU - Dessanti, Paola AU - Rotllant, David AU - Navarro, Xavier AU - Herrando-Grabulosa, Mireia AU - Buesa, Carlos AU - Maes, Tamara PY - 2022 DO - 10.3390/pharmaceutics14071420 SN - 1999-4923 UR - http://hdl.handle.net/10668/21554 T2 - Pharmaceutics AB - Lysine specific demethylase 1 (LSD1; also known as KDM1A), is an epigenetic modulator that modifies the histone methylation status. KDM1A forms a part of protein complexes that regulate the expression of genes involved in the onset and progression of... LA - en PB - MDPI AG KW - KDM1A KW - epigenetics KW - multiple sclerosis KW - neuroinflammation KW - vafidemstat KW - Glutamates KW - Histone Demethylases KW - Epigenesis, Genetic KW - Lysine KW - Sphingosine-1-Phosphate Receptors KW - Multiple Sclerosis KW - Neurodegenerative Diseases TI - Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis. TY - research article VL - 14 ER -