RT Journal Article
T1 Zinc and silica are active components to efficiently treat in vitro simulated eroded dentin.
A1 Osorio, Raquel
A1 Toledano-Osorio, Manuel
A1 Osorio, Estrella
A1 Aguilera, Fátima S
A1 Padilla-Mondéjar, Sussette
A1 Toledano, Manuel
K1 Dentin
K1 Mechanical properties
K1 Raman
K1 Silica
K1 Zinc
AB Biomaterials for treating dentin hypersensitivity and dentin wear were evaluated to efficiently occlude the dentinal tubules and to increase dentin resistance to abrasion. Twenty-four dentin surfaces were treated with EDTA to expose dentinal tubules and were (1) non-brushed, (2) brushed with distilled water, or with pastes containing (3) monetite, (4) brushite, (5) Zn-monetite, (6) Zn-brushite, (7) Silica-brushite, and (8) NovaMin®. Topographical, nanomechanical, and chemical analysis were assessed on dentin surfaces (n = 3) after artificial saliva immersion for 24 h, and after citric acid challenge. Twenty-one further dentin specimens were created to evaluate dentin permeability after brushing, saliva storage, and acid application (n = 3). ANOVA, Student-Newman-Keuls (p  Particles containing major proportion of silica attained intratubular occlusion by carbonate crystals (Raman carbonate peak heights 15.17 and 19.24 au; complex modulus 110 and 140 GPa, at intratubular dentin). When brushing with pastes containing higher proportion of silica or zinc, phosphate calcium compounds were encountered into tubules and over dentin surfaces (Raman intratubular phosphate peak heights 49 to 70 au, and at the intertubular dentin 78 to 92). The formed carbonated apatite and calcium phosphate layer were resistant to citric acid application. Zinc compounds drastically increased tubule occlusion, decreased dentin permeability (up to 30%), and augmented mechanical properties at the intertubular dentin (90-130 GPa); it was maintained after acid challenging. Zinc-containing pastes occluded dentinal tubules and improved dentin mechanical properties. Using zinc as an active component to treat eroded dentin is encouraged.
PB Springer
YR 2018
FD 2018-01-29
LK http://hdl.handle.net/10668/12086
UL http://hdl.handle.net/10668/12086
LA en
NO Osorio R, Toledano-Osorio M, Osorio E, Aguilera FS, Padilla-Mondéjar S, Toledano M. Zinc and silica are active components to efficiently treat in vitro simulated eroded dentin. Clin Oral Investig. 2018 Nov;22(8):2859-2870.
NO Projects MAT2014-52036-P and RTC-2014-1731-1, both supported by the Ministry of Economy and Competitiveness and EuropeanRegional Development Fund.
DS RISalud
RD Apr 19, 2025