%0 Journal Article
%A Cortes-Vicente, Elena
%A Alvarez-Velasco, Rodrigo
%A Segovia, Sonia
%A Paradas, Carmen
%A Casasnovas, Carlos
%A Guerrero-Sola, Antonio
%A Pardo, Julio
%A Ramos-Fransi, Alba
%A Sevilla, Teresa
%A Lopez-de-Munain, Adolfo
%A Gomez, Maria Teresa
%A Jerico, Ivonne
%A Gutierrez-Gutierrez, Gerardo
%A Pelayo-Negro, Ana Lara
%A Martin, Maria Asuncion
%A Mendoza, Maria Dolores
%A Moris, German
%A Rojas-Garcia, Ricard
%A Diaz-Manera, Jordi
%A Querol, Luis
%A Gallardo, Eduard
%A Velez, Beatriz
%A Alberti, Maria Antonia
%A Galan, Luciía
%A Garcia-Sobrino, Tania
%A Martinez-Piñeiro, Alicia
%A Lozano-Veintimilla, Ana
%A Fernandez-Torron, Roberto
%A Cano-Abascal, Angel
%A Illa, Isabel
%T Clinical and therapeutic features of myasthenia gravis in adults based on age at onset.
%D 2020
%U http://hdl.handle.net/10668/15126
%X To describe the characteristics of patients with very-late-onset myasthenia gravis (MG). This observational cross-sectional multicenter study was based on information in the neurologist-driven Spanish Registry of Neuromuscular Diseases (NMD-ES). All patients were >18 years of age at onset of MG and onset occurred between 2000 and 2016 in all cases. Patients were classified into 3 age subgroups: early-onset MG (age at onset 18 years of age at onset of MG and onset occurred between 2000 and 2016 in all cases. Patients were classified into 3 age subgroups: early-onset MG (age at onset  A total of 939 patients from 15 hospitals were included: 288 (30.7%) had early-onset MG, 227 (24.2%) late-onset MG, and 424 (45.2%) very-late-onset MG. The mean follow-up was 9.1 years (SD 4.3). Patients with late onset and very late onset were more frequently men (p  Patients with MG are primarily ≥65 years of age with anti-AChR antibodies and no thymoma. Although patients with very-late-onset MG may present life-threatening events at onset, they achieve a good outcome with fewer immunosuppressants when diagnosed and treated properly.
%K Age of Onset
%K Female
%K Male
%K Myasthenia Gravis
%~