RT Journal Article
T1 Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations.
A1 Alcala-Santiago, Angela
A1 Rodriguez-Barranco, Miguel
A1 Rava, Marta
A1 Jimenez-Sousa, Maria Angeles
A1 Gil, Angel
A1 Sanchez-Perez, Maria-Jose
A1 Molina-Montes, Esther
K1 COVID-19
K1 SARS-CoV-2
K1 computational biology
K1 genes
K1 nutrition
K1 vitamin D
AB Vitamin D (VD) is a fat-soluble vitamin, and pivotal for maintaining health. Several genetic markers have been related to a deficient VD status; these markers could confer an increased risk to develop osteoporosis and other chronic diseases. A VD deficiency could also be a determinant of a severe COVID-19 disease. This study aimed to interrogate genetic/biological databases on the biological implications of a VD deficiency and its association with diseases, to further explore its link with COVID-19. The genetic variants of both a VD deficiency and COVID-19 were identified in the genome-wide association studies (GWAS) catalog and other sources. We conducted enrichment analyses (considering corrected p-values
PB MDPI AG
YR 2022
FD 2022-11-14
LK http://hdl.handle.net/10668/21217
UL http://hdl.handle.net/10668/21217
LA en
NO Alcalá-Santiago Á, Rodríguez-Barranco M, Rava M, Jiménez-Sousa MÁ, Gil Á, Sánchez MJ, et al.  Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations. Int J Mol Sci. 2022 Nov 17;23(22):14256.
NO This research was funded by Project PECOVID-0200-2020, funded by Consejería de Salud dela Junta de Andalucía and co-funded by the European Regional Development Fund (ERDF-FEDER).
DS RISalud
RD Apr 17, 2025