%0 Journal Article %A Alcala-Santiago, Angela %A Rodriguez-Barranco, Miguel %A Rava, Marta %A Jimenez-Sousa, Maria Angeles %A Gil, Angel %A Sanchez-Perez, Maria-Jose %A Molina-Montes, Esther %T Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations. %D 2022 %U http://hdl.handle.net/10668/21217 %X Vitamin D (VD) is a fat-soluble vitamin, and pivotal for maintaining health. Several genetic markers have been related to a deficient VD status; these markers could confer an increased risk to develop osteoporosis and other chronic diseases. A VD deficiency could also be a determinant of a severe COVID-19 disease. This study aimed to interrogate genetic/biological databases on the biological implications of a VD deficiency and its association with diseases, to further explore its link with COVID-19. The genetic variants of both a VD deficiency and COVID-19 were identified in the genome-wide association studies (GWAS) catalog and other sources. We conducted enrichment analyses (considering corrected p-values %K COVID-19 %K SARS-CoV-2 %K computational biology %K genes %K nutrition %K vitamin D %~