RT Journal Article
T1 Non-animal-derived monoclonal antibodies are not ready to substitute current hybridoma technology.
A1 Gonzalez-Fernandez, Africa
A1 Bermudez-Silva, Francisco J
A1 Lopez-Hoyos, Marcos
A1 Cobaleda, Cesar
A1 Montoliu, Lluis
A1 Del-Val, Margarita
A1 Leech, Kirk
K1 Animal Testing Alternatives
K1 Animals
K1 Antibodies, Monoclonal
AB We write on behalf of the COSCE (Confederation of Spanish Scientific societies) Transparency Agreement on Animal Research, supported by the EARA (European Animal Research Association). In May 2020, the European Commission’s Joint Research Centre (EC-JRC) released a recommendation on the development of non-animal-derived antibodies, urging government authorities, funding agencies and publishers to endorse the use of these antibodies to improve scientific reproducibility1. These recommendations were based on the work done by the Scientific Advisory Committee (ESAC) of the European Union Reference Laboratory for alternatives to animal testing (EURL ECVAM). Recent correspondence to Nature and Nature Methods claims that non-animal antibodies are ready to replace animal-derived ones in all known applications.
PB Nature Publishing Group
YR 2020
FD 2020
LK http://hdl.handle.net/10668/16371
UL http://hdl.handle.net/10668/16371
LA en
NO González-Fernández Á, Bermúdez Silva FJ, López-Hoyos M, Cobaleda C, Montoliu L, Del Val M, et al. Non-animal-derived monoclonal antibodies are not ready to substitute current hybridoma technology. Nat Methods. 2020 Nov;17(11):1069-1070
DS RISalud
RD Apr 11, 2025