TY  - JOUR
AU  - Cabeza, Laura
AU  - Ortiz, Raúl
AU  - Arias, José L
AU  - Prados, Jose
AU  - Ruiz Martínez, Maria Adolfina
AU  - Entrena, José M
AU  - Luque, Raquel
AU  - Melguizo, Consolación
PY  - 2015
DO  - 10.2147/IJN.S74378
SN  - 1176-9114
UR  - http://hdl.handle.net/10668/2099
T2  - International Journal of Nanomedicine
AB  - The use of doxorubicin (DOX), one of the most effective antitumor molecules in the treatment of metastatic breast cancer, is limited by its low tumor selectivity and its severe side effects. Colloidal carriers based on biodegradable...
LA  - en
PB  - Dove Medical Press
KW  - Biodegradable polymer
KW  - Carcinoma
KW  - Cytotoxicity
KW  - Chemotherapeutic drug
KW  - Drug delivery
KW  - Nanopolymer
KW  - Adsorción
KW  - Animales
KW  - Neoplasias de la mama
KW  - Línea celular tumoral
KW  - Cianoacrilatos
KW  - Preparaciones de acción retardada
KW  - Doxorrubicina
KW  - Enbucrilato
KW  - Humanos
KW  - Concentración 50 inhibidora
KW  - Ratones consanguíneos C57BL
KW  - Nanopartículas
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Physicochemical Phenomena::Physicochemical Processes::Adsorption
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Acrylates::Cyanoacrylates
KW  - Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations::Dosage Forms::Delayed-Action Preparations
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Anthracyclines::Daunorubicin::Doxorubicin
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Acrylates::Cyanoacrylates::Enbucrilate
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Toxicity Tests::Inhibitory Concentration 50
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Animal Population Groups::Animals, Inbred Strains::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Technology, Industry, Agriculture::Technology, Industry, and Agriculture::Manufactured Materials::Nanostructures::Nanoparticles
TI  - Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles.
TY  - research article
ER  -