TY - JOUR AU - Campo, P AU - Rodríguez, F AU - Sánchez-García, S AU - Barranco, P AU - Quirce, S AU - Pérez-Francés, C AU - Gómez-Torrijos, E AU - Cárdenas, R AU - Olaguibel, J M AU - Delgado, J PY - 2013 SN - 1018-9068 UR - http://hdl.handle.net/10668/1532 T2 - Journal of investigational allergology & clinical immunology AB - El asma grave es una enfermedad heterogénea que constituye entre un 5-10% de los sujetos asmáticos, pero representan un porcentaje significativo del consumo de los recursos sanitarios. El asma grave se caracteriza por precisar tratamiento con altas... AB - Severe asthma is a heterogeneous disease that affects only 5%-10% of asthmatic patients, although it accounts for a significant percentage of the consumption of health care resources. Severe asthma is characterized by the need for treatment with high... LA - en PB - Esmon Publicidad KW - Severe asthma KW - Biomarkers KW - Endotype KW - Phenotype KW - Treatment KW - Asma grave KW - Biomarcadores KW - Endotipo KW - Fenotipo KW - Tratamiento KW - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Respiratory System Agents::Anti-Asthmatic Agents KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal KW - Medical Subject Headings::Diseases::Respiratory Tract Diseases::Bronchial Diseases::Asthma KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Respiratory System Agents::Anti-Asthmatic Agents::Bronchodilator Agents KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Child KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Child::Child, Preschool KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Infant KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Severity of Illness Index KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adolescent TI - Phenotypes and endotypes of uncontrolled severe asthma: new treatments. TY - review article ER -