TY - JOUR AU - Suarez-Pereira, I. AU - Garcia-Dominguez, I. AU - Bravo, L. AU - Santiago, M. AU - Garcia-Revilla, J. AU - Espinosa-Oliva, A. M. AU - Alonso-Bellido, I. M. AU - Lopez-Martin, C. AU - Perez-Villegas, E. M. AU - Armengol, J. A. AU - Berrocoso, E. AU - Venero, J. L. AU - de Pablos, R. M. AU - Ruiz, R. PY - 2022 DO - 10.3389/fcell.2022.839715 SN - 2296-634X UR - http://hdl.handle.net/10668/20531 T2 - Frontiers in cell and developmental biology AB - In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive and nonfunctional synapses... LA - en PB - Frontiers Research Foundation KW - Autism spectrum disorder KW - Dopaminergic system KW - Caspase 8 KW - Electron microscopy KW - Synapsis KW - Behavioral test KW - Cell-death KW - Spectrum disorders KW - Substantia-nigra KW - Apoptosis KW - Modulation KW - Expression KW - Induction KW - Necroptosis KW - Receptors KW - Cytokines KW - Dopamine KW - Caspase 8 KW - Dopaminergic neurons KW - Autism spectrum disorder KW - Microscopy, electron KW - Neurotransmitter agents KW - Recombination, genetic KW - Tyrosine 3-monooxygenase TI - The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior TY - research article VL - 10 ER -