TY - JOUR AU - Ayuso, Pedro AU - García-Martín, Elena AU - Cornejo-García, José A. AU - Agúndez, José A G. AU - Ladero, José María PY - 2021 DO - 10.3390/jpm11050409 UR - http://hdl.handle.net/10668/3961 T2 - Journal of Personalized Medicine AB - Alcohol-related liver disease (ARLD) is a major public health issue caused by excessive alcohol consumption. ARLD encompasses a wide range of chronic liver lesions, alcohol-related liver cirrhosis being the most severe and harmful state. Variations in... LA - en PB - MDPI KW - Alcohol-related liver disease KW - Cirrhosis KW - Single nucleotide variations KW - Copy number variations KW - Alcohol dehydrogenase KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Hemeproteins::Cytochromes::Cytochrome P-450 Enzyme System::Aryl Hydrocarbon Hydroxylases::Cytochrome P-450 CYP2E1 KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Genomic Structural Variation::DNA Copy Number Variations KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Sequence Deletion::Gene Deletion KW - Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Drinking Behavior::Alcohol Drinking KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Liver Neoplasms KW - Medical Subject Headings::Diseases::Digestive System Diseases::Liver Diseases::Liver Cirrhosis KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Analysis of Variance::Multivariate Analysis KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides TI - Genetic Variants of Alcohol Metabolizing Enzymes and Alcohol-Related Liver Cirrhosis Risk TY - research article ER -