RT Journal Article
T1 Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI).
A1 Sideli, Lucia
A1 Schimmenti, Adriano
A1 La-Barbera, Daniele
A1 La-Cascia, Caterina
A1 Ferraro, Laura
A1 Aas, Monica
A1 Alameda, Luis
A1 Velthorst, Eva
A1 Fisher, Helen L
A1 Caretti, Vincenzo
A1 Trotta, Giulia
A1 Tripoli, Giada
A1 Quattrone, Diego
A1 Gayer-Anderson, Charlotte
A1 Seminerio, Fabio
A1 Sartorio, Crocettarachele
A1 Marrazzo, Giovanna
A1 Lasalvia, Antonio
A1 Tosato, Sarah
A1 Tarricone, Ilaria
A1 Berardi, Domenico
A1 D'Andrea, Giuseppe
A1 Arango, Celso
A1 Arrojo, Manuel
A1 Bernardo, Miguel
A1 Bobes, Julio
A1 Sanjuan, Julio
A1 Santos, Jose Luis
A1 Menezes, Paulo Rossi
A1 Del-Ben, Cristina Marta
A1 Jongsma, Hannah E
A1 Jones, Peter B
A1 Kirkbride, James B
A1 Llorca, Pierre-Michel
A1 Tortelli, Andrea
A1 Pignon, Baptiste
A1 de Haan, Lieuwe
A1 Selten, Jean-Paul
A1 Van Os, Jim
A1 Rutten, Bart P
A1 Di Forti, Marta
A1 Morgan, Craig
A1 Murray, Robin M
K1 IQ
K1 childhood abuse
K1 childhood neglect
K1 psychosis
K1 schizophrenia
AB Evidence suggests that childhood maltreatment (ie, childhood abuse and childhood neglect) affects educational attainment and cognition. However, the association between childhood maltreatment and Intelligence Quotient (IQ) seems stronger among controls compared to people with psychosis. We hypothesised that: the association between childhood maltreatment and poor cognition would be stronger among community controls than among people with first-episode of psychosis (FEP); compared to abuse, neglect would show stronger associations with educational attainment and cognition; the association between childhood maltreatment and IQ would be partially accounted for by other risk factors; and the association between childhood maltreatment, educational attainment, and IQ would be stronger among patients with affective psychoses compared to those with nonaffective psychoses. 829 patients with FEP and 1283 community controls from 16 EU-GEI sites were assessed for child maltreatment, education attainment, and IQ. In both the FEP and control group, childhood maltreatment was associated with lower educational attainment. The association between childhood maltreatment and lower IQ was robust to adjustment for confounders only among controls. Whereas childhood neglect was consistently associated with lower attainment and IQ in both groups, childhood abuse was associated with IQ only in controls. Among both patients with affective and nonaffective psychoses, negative associations between childhood maltreatment and educational attainment were observed, but the crude association with IQ was only evident in affective psychoses. Our findings underscore the role of childhood maltreatment in shaping academic outcomes and cognition of people with FEP as well as controls.
PB Oxford University Press
YR 2022
FD 2022-02-09
LK http://hdl.handle.net/10668/19836
UL http://hdl.handle.net/10668/19836
LA en
NO Sideli L, Schimmenti A, La Barbera D, La Cascia C, Ferraro L, Aas M, et al. Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI). Schizophr Bull. 2022 May 7;48(3):575-589.
DS RISalud
RD Apr 7, 2025