RT Journal Article
T1 High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma.
A1 Marhuenda-Muñoz, María
A1 Rinaldi de Alvarenga, José Fernando
A1 Hernáez, Álvaro
A1 Tresserra-Rimbau, Anna
A1 Martínez-González, Miguel Ángel
A1 Salas-Salvadó, Jordi
A1 Corella, Dolores
A1 Malcampo, Mireia
A1 Martínez, José Alfredo
A1 Alonso-Gómez, Ángel M
A1 Wärnberg, Julia
A1 Vioque, Jesús
A1 Romaguera, Dora
A1 López-Miranda, José
A1 Estruch, Ramón
A1 Tinahones, Francisco J
A1 Lapetra, José
A1 Serra-Majem, J Lluís
A1 Bueno-Cavanillas, Aurora
A1 Tur, Josep A
A1 Sánchez, Vicente Martín
A1 Pintó, Xavier
A1 Delgado-Rodríguez, Miguel
A1 Matía-Martín, Pilar
A1 Vidal, Josep
A1 Vázquez, Clotilde
A1 Daimiel, Lidia
A1 Ros, Emilio
A1 Serra-Mir, Mercè
A1 Vázquez-Ruiz, Zenaida
A1 Nishi, Stephanie K
A1 Sorlí, Jose V
A1 Zomeño, María Dolores
A1 Zulet, María Angeles
A1 Vaquero-Luna, Jessica
A1 Carabaño-Moral, Rosa
A1 Notario-Barandiaran, Leyre
A1 Morey, Marga
A1 García-Ríos, Antonio
A1 Gómez-Pérez, Ana M
A1 Santos-Lozano, José Manuel
A1 Buil-Cosiales, Pilar
A1 Basora, Josep
A1 Portolés, Olga
A1 Schröder, Helmut
A1 Abete, Itziar
A1 Salaverria-Lete, Itziar
A1 Toledo, Estefanía
A1 Babio, Nancy
A1 Fitó, Montse
A1 Martínez-Huélamo, Miriam
A1 Lamuela-Raventós, Rosa M
K1 Mediterranean diet
K1 PREDIMED-Plus study
K1 bioactive compounds
K1 dietary fats
K1 liquid chromatography
K1 mass spectrometry
K1 matrix effect absorption
K1 phytochemicals
K1 plasma carotenoids
AB Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 μmol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (-2.69 μmol/L (-5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.
SN 2076-3921
YR 2021
FD 2021-03-17
LK https://hdl.handle.net/10668/25812
UL https://hdl.handle.net/10668/25812
LA en
DS RISalud
RD Apr 6, 2025