TY - JOUR AU - Hernandez, Ivo H AU - Torres-Peraza, Jesus AU - Santos-Galindo, Maria AU - Ramos-Moron, Eloisa AU - Fernandez-Fernandez, M Rosario AU - Perez-Alvarez, Maria J AU - Miranda-Vizuete, Antonio AU - Lucas, Jose J PY - 2017 DO - 10.1007/s00401-017-1770-2 UR - http://hdl.handle.net/10668/11549 T2 - Acta neuropathologica AB - Activating transcription factor-5 (ATF5) is a stress-response transcription factor induced upon different cell stressors like fasting, amino-acid limitation, cadmium or arsenite. ATF5 is also induced, and promotes transcription of anti-apoptotic... LA - en PB - Springer KW - ATF5 KW - ER stress KW - Huntington’s disease KW - MCL1 KW - Neuroprotection KW - UPR KW - Activating Transcription Factors KW - Animals KW - Apoptosis KW - Caenorhabditis elegans KW - Caenorhabditis elegans Proteins KW - Cell Line, Tumor KW - Disease Models, Animal KW - Endoplasmic Reticulum Stress KW - Humans KW - Huntingtin Protein KW - Huntington Disease KW - Inclusion Bodies KW - Mice, Transgenic KW - Neurons KW - Neuroprotection KW - Peptides TI - The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease. TY - research article VL - 134 ER -