RT Journal Article
T1 Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey
A1 Pironi, Loris
A1 Steiger, Ezra
A1 Joly, Francisca
A1 Jeppesen, Palle B.
A1 Wanten, Geert
A1 Sasdelli, Anna S.
A1 Chambrier, Cecile
A1 Aimasso, Umberto
A1 Mundi, Manpreet S.
A1 Szczepanek, Kinga
A1 Jukes, Amelia
A1 Theilla, Miriam
A1 Kunecki, Marek
A1 Daniels, Joanne
A1 Serlie, Mireille
A1 Poullenot, Florian
A1 Cooper, Sheldon C.
A1 Rasmussen, Henrik H.
A1 Compher, Charlene
A1 Seguy, David
A1 Crivelli, Adriana
A1 Santarpia, Lidia
A1 Guglielmi, Francesco W.
A1 Kozjek, Nada Rotovnik
A1 Schneider, Stephane M.
A1 Ellegard, Lars
A1 Thibault, Ronan
A1 Matras, Przemyslaw
A1 Matysiak, Konrad
A1 Van Gossum, Andre
A1 Forbes, Alastair
A1 Wyer, Nicola
A1 Taus, Marina
A1 Virgili, Nuria M.
A1 O'Callaghan, Margie
A1 Chapman, Brooke
A1 Osland, Emma
A1 Cuerda, Cristina
A1 Udvarhelyi, Gabor
A1 Jones, Lynn
A1 Lee, Andre D. Won
A1 Masconale, Luisa
A1 Orlandoni, Paolo
A1 Spaggiari, Corrado
A1 Diez, Marta Bueno
A1 Doitchinova-Simeonova, Maryana
A1 Serralde-Zuniga, Aurora E.
A1 Olveira, Gabriel
A1 Krznaric, Zeljko
A1 Czako, Laszlo
A1 Kekstas, Gintautas
A1 Sanz-Paris, Alejandro
A1 Petrina Jauregui, Ma Estrella
A1 Murillo, Ana Zugasti
A1 Schafer, Eszter
A1 Arends, Jann
A1 Suarez-Llanos, Jose P.
A1 Su, P.
A1 Youssef, Nader N.
A1 Brillanti, Giorgia
A1 Nardi, Elena
A1 Lal, Simon
A1 Home Artificial Nutrition Chronic, 
A1 European Soc Clinical Nutr Metab, 
K1 Short bowel syndrome
K1 Intestinal failure
K1 Intravenous supplementation
K1 Home parenteral nutrition
K1 Epidemiology
K1 Definitions
K1 Teduglutide
K1 Length
AB Background and aims: The case-mix of patients with intestinal failure due to short bowel syndrome (SBSIF) can differ among centres and may also be affected by the timeframe of data collection. Therefore, the ESPEN international multicenter cross-sectional survey was analyzed to compare the characteristics of SBS-IF cohorts collected within the same timeframe in different countries.Methods: The study included 1880 adult SBS-IF patients collected in 2015 by 65 centres from 22 countries. The demographic, nutritional, SBS type (end jejunostomy, SBS-J; jejuno-colic anastomosis, SBS-JC; jejunoileal anastomosis with an intact colon and ileocecal valve, SBS-JIC), underlying disease and intravenous supplementation (IVS) characteristics were analyzed. IVS was classified as fluid and electrolyte alone (FE) or parenteral nutrition admixture (PN). The mean daily IVS volume, calculated on a weekly basis, was categorized as 3 L/day.Results: In the entire group: 60.7% were females and SBS-J comprised 60% of cases, while mesenteric ischaemia (MI) and Crohn' disease (CD) were the main underlying diseases. IVS dependency was longer than 3 years in around 50% of cases; IVS was infused >5 days/week in 75% and FE in 10% of cases. Within the SBS-IF cohort: CD was twice and thrice more frequent in SBS-J than SBS-JC and SBS-JIC, respectively, while MI was more frequent in SBS-JC and SBS-JIC. Within countries: SBS-J represented 75% or more of patients in UK and Denmark and 50-60% in the other countries, except Poland where SBS-JC prevailed. CD was the main underlying disease in UK, USA, Denmark and The Netherlands, while MI prevailed in France, Italy and Poland.Conclusions: SBS-IF type is primarily determined by the underlying disease, with significant variation between countries. These novel data will be useful for planning and managing both clinical activity and research studies on SBS. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
PB Elsevier
SN 2405-4577
YR 2021
FD 2021-10-04
LK https://hdl.handle.net/10668/24360
UL https://hdl.handle.net/10668/24360
LA en
DS RISalud
RD Apr 4, 2025