RT Journal Article T1 Letter: mechanistic target of rapamycin inhibitors as adjuvant therapy for patients with hepatocellular carcinoma undergoing liver transplantation. A1 Rodriguez-Peralvarez, Manuel A1 Amado, Victor A1 de la Mata, Manuel AB We read with great interest the meta‐analysis by Grigg et al,1 which evaluated the role of the mechanistic target of rapamycin (mTOR) inhibitors (sirolimus or everolimus) in patients with hepatocellular carcinoma (HCC) undergoing liver transplantation (LT). The authors found that mTOR‐inhibitor based immunosuppression was associated with prolonged recurrence‐free and overall survival. Although these findings could motivate the reader to systematically prescribe mTOR inhibitors in patients with HCC, there are some important considerations to be taken into account first. PB Wiley-Blackwell Publishing YR 2019 FD 2019 LK http://hdl.handle.net/10668/14335 UL http://hdl.handle.net/10668/14335 LA en NO Rodríguez-Perálvarez M, Amado V, de la Mata M. Letter: mechanistic target of rapamycin inhibitors as adjuvant therapy for patients with hepatocellular carcinoma undergoing liver transplantation. Aliment Pharmacol Ther. 2019 Aug;50(4):478-479 DS RISalud RD Apr 9, 2025