TY - JOUR AU - Sanchez-Varo, Raquel AU - Sanchez-Mejias, Elisabeth AU - Fernandez-Valenzuela, Juan Jose AU - De Castro, Vanessa AU - Mejias-Ortega, Marina AU - Gomez-Arboledas, Angela AU - Jimenez, Sebastian AU - Sanchez-Mico, Maria Virtudes AU - Trujillo-Estrada, Laura AU - Moreno-Gonzalez, Ines AU - Baglietto-Vargas, David AU - Vizuete, Marisa AU - Davila, Jose Carlos AU - Vitorica, Javier AU - Gutierrez, Antonia PY - 2021 DO - 10.3389/fnins.2021.752594 SN - 1662-4548 UR - https://hdl.handle.net/10668/25411 T2 - Frontiers in neuroscience AB - Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that progress to dementia. In this sense, synaptic dysfunction and loss have been established as the pathological features that best... LA - en KW - Alzheimer’s disease KW - amyloid KW - hippocampus KW - oligomers KW - synaptic pathology KW - transgenic mice (Tg) TI - Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis. TY - research article VL - 15 ER -