RT Journal Article
T1 Trabecular Bone Score, Bone Mineral Density and Bone Markers in Patients with Primary Hyperparathyroidism 2 Years After Parathyroidectomy.
A1 Miguel, Gonzalo Allo
A1 Carranza, Federico Hawkins
A1 Rodríguez, Juan Carlos Romero
A1 Ramos, Mercedes Aramendi
A1 Pablos, David Lora
A1 Herrero, Eduardo Ferrero
A1 Díaz-Guerra, Guillermo Martínez
AB Following a parathyroidectomy there is a bone mineral density (BMD) improvement in patients with primary hyperparathyroidism. However, data of bone microarchitecture are scarce. Trabecular bone score (TBS) estimates bone microarchitecture and could provide valuable information in those patients. The aim of this study is to assess TBS changes 2 years after successful surgery in a group of patients with primary hyperparathyroidism and correlate these results with changes in BMD and bone turnover markers. This is a prospective study including 32 patients. In all participants BMD and TBS were measured, before and 24 months after surgery. Biochemical data: serum calcium, PTH, 25-OH-vitamin D, beta-crosslaps, bone alkaline phosphatase, and osteocalcin. 25 female and 7 male patients, mean age 64.6±12.4 years, were included in the study. At baseline, BMD was low at: lumbar spine (T-score -2.19±1.31), total hip (-1.33±1.12), femoral neck (-1.75±0.84), and distal one-third radius (-2.74±1.68). Baseline TBS showed partially degraded microarchitecture (1.180±0.130). After parathyroidectomy lumbar spine BMD increased significantly (5.3±13.0%, p
YR 2019
FD 2019-03-12
LK https://hdl.handle.net/10668/25391
UL https://hdl.handle.net/10668/25391
LA en
DS RISalud
RD Apr 7, 2025