TY  - JOUR
AU  - García-Fuentes, Eduardo
AU  - Santiago-Fernández, Concepción
AU  - Gutiérrez-Repiso, Carolina
AU  - Mayas, María D
AU  - Oliva-Olivera, Wilfredo
AU  - Coín-Aragüez, Leticia
AU  - Alcaide, Juan
AU  - Ocaña-Wilhelmi, Luis
AU  - Vendrell, Joan
AU  - Tinahones, Francisco J
AU  - Garrido-Sánchez, Lourdes
PY  - 2015
DO  - 10.1186/s12967-015-0732-5
UR  - http://hdl.handle.net/10668/2449
T2  - Journal of Translational Medicine
AB  - BACKGROUND:A key role for HIF-1α in the promotion and maintenance of dietary obesity has been proposed. We analyzed the association between hypoxia and de novo lipogenesis in human adipose tissue.METHODS:We studied HIF-1α mRNA and protein expression...
LA  - en
PB  - Biomed Central
KW  - Adipogénesis
KW  - Tejido adiposo
KW  - Índice de masa corporal
KW  - Dieta
KW  - Ayuno
KW  - Factor 1 inducible por hipoxia
KW  - Resistencia a la insulina
KW  - Grasa intraabdominal
KW  - Lipogénesis
KW  - Ratones
KW  - Humanos
KW  - Obesidad mórbida
KW  - PPAR gamma
KW  - ARN mensajero
KW  - Proteína 1 de unión a elementos reguladores de esteroles
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Adipogenesis
KW  - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet::Fasting
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic Helix-Loop-Helix Transcription Factors::Hypoxia-Inducible Factor 1::Hypoxia-Inducible Factor 1, alpha Subunit
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Insulin Resistance
KW  - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue::Adipose Tissue, White::Abdominal Fat::Intra-Abdominal Fat
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipogenesis
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Peroxisome Proliferator-Activated Receptors::PPAR gamma
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic-Leucine Zipper Transcription Factors::Basic Helix-Loop-Helix Leucine Zipper Transcription Factors::Sterol Regulatory Element...
TI  - Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue.
TY  - research article
ER  -