RT Journal Article
T1 Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii.
A1 Fernandez-Garcia, Laura
A1 Ambroa, Antón
A1 Blasco, Lucia
A1 Bleriot, Ines
A1 López, Maria
A1 Alvarez-Marin, Rocio
A1 Fernández-Cuenca, Felipe
A1 Martinez-Martinez, Luis
A1 Vila, Jordi
A1 Rodríguez-Baño, Jesús
A1 Garnacho-Montero, Jose
A1 Cisneros, Jose Miguel
A1 Pascual, Alvaro
A1 Pachón, Jeronimo
A1 Bou, German
A1 Smani, Younes
A1 Tomás, Maria
K1 Acinetobacter
K1 bacteraemia
K1 pneumonia
K1 quorum
K1 sensing/quenching
AB Acinetobacter baumannii (Ab) is one of the most important pathogens associated with nosocomial infections, especially pneumonia. Interest in the Quorum network, i.e., Quorum Sensing (QS)/Quorum Quenching (QQ), in this pathogen has grown in recent years. The Quorum network plays an important role in regulating diverse virulence factors such as surface motility and bacterial competition through the type VI secretion system (T6SS), which is associated with bacterial invasiveness. In the present study, we investigated 30 clinical strains of A. baumannii isolated in the "II Spanish Study of A. baumannii GEIH-REIPI 2000-2010" (Genbank Umbrella Bioproject PRJNA422585), a multicentre study describing the relationship between the Quorum network in A. baumannii and the development of pneumonia and associated bacteraemia. Expression of the aidA gene (encoding the AidA protein, QQ enzyme) was lower (P
SN 1664-302X
YR 2018
FD 2018-12-17
LK https://hdl.handle.net/10668/27968
UL https://hdl.handle.net/10668/27968
LA en
DS RISalud
RD Apr 6, 2025