TY - JOUR AU - Gavilan, Maria P AU - Gandolfo, Pablo AU - Balestra, Fernando R AU - Arias, Francisco AU - Bornens, Michel AU - Rios, Rosa M PY - 2018 DO - 10.15252/embr.201845942 UR - http://hdl.handle.net/10668/12957 T2 - EMBO reports AB - Here, we address the regulation of microtubule nucleation during interphase by genetically ablating one, or two, of three major mammalian γ-TuRC-binding factors namely pericentrin, CDK5Rap2, and AKAP450. Unexpectedly, we find that while all of them... LA - en KW - PCNT KW - AKAP450 KW - Golgi apparatus KW - centrosome KW - microtubule nucleation KW - A Kinase Anchor Proteins KW - Antigens KW - CRISPR-Cas Systems KW - Cell Cycle Proteins KW - Cell Line KW - Centrosome KW - Chromosomal Proteins, Non-Histone KW - Cytoskeletal Proteins KW - Gene Knockout Techniques KW - Golgi Apparatus KW - Humans KW - Interphase KW - Intracellular Signaling Peptides and Proteins KW - Microtubules KW - Nerve Tissue Proteins KW - Tubulin TI - The dual role of the centrosome in organizing the microtubule network in interphase. TY - research article VL - 19 ER -