RT Journal Article
T1 Discovery of common and rare genetic risk variants for colorectal cancer.
A1 Huyghe, Jeroen R
A1 Bien, Stephanie A
A1 Harrison, Tabitha A
A1 Kang, Hyun Min
A1 Chen, Sai
A1 Schmit, Stephanie L
A1 Conti, David V
A1 Qu, Conghui
A1 Jeon, Jihyoun
A1 Edlund, Christopher K
A1 Greenside, Peyton
A1 Wainberg, Michael
A1 Schumacher, Fredrick R
A1 Smith, Joshua D
A1 Levine, David M
A1 Nelson, Sarah C
A1 Sinnott-Armstrong, Nasa A
A1 Albanes, Demetrius
A1 Alonso, M Henar
A1 Anderson, Kristin
A1 Arnau-Collell, Coral
A1 Arndt, Volker
A1 Bamia, Christina
A1 Banbury, Barbara L
A1 Baron, John A
A1 Berndt, Sonja I
A1 Bézieau, Stéphane
A1 Bishop, D Timothy
A1 Boehm, Juergen
A1 Boeing, Heiner
A1 Brenner, Hermann
A1 Brezina, Stefanie
A1 Buch, Stephan
A1 Buchanan, Daniel D
A1 Burnett-Hartman, Andrea
A1 Butterbach, Katja
A1 Caan, Bette J
A1 Campbell, Peter T
A1 Carlson, Christopher S
A1 Castellví-Bel, Sergi
A1 Chan, Andrew T
A1 Chang-Claude, Jenny
A1 Chanock, Stephen J
A1 Chirlaque, Maria-Dolores
A1 Cho, Sang Hee
A1 Connolly, Charles M
A1 Cross, Amanda J
A1 Cuk, Katarina
A1 Curtis, Keith R
A1 de la Chapelle, Albert
A1 Doheny, Kimberly F
A1 Duggan, David
A1 Easton, Douglas F
A1 Elias, Sjoerd G
A1 Elliott, Faye
A1 English, Dallas R
A1 Feskens, Edith J M
A1 Figueiredo, Jane C
A1 Fischer, Rocky
A1 FitzGerald, Liesel M
A1 Forman, David
A1 Gala, Manish
A1 Gallinger, Steven
A1 Gauderman, W James
A1 Giles, Graham G
A1 Gillanders, Elizabeth
A1 Gong, Jian
A1 Goodman, Phyllis J
A1 Grady, William M
A1 Grove, John S
A1 Gsur, Andrea
A1 Gunter, Marc J
A1 Haile, Robert W
A1 Hampe, Jochen
A1 Hampel, Heather
A1 Harlid, Sophia
A1 Hayes, Richard B
A1 Hofer, Philipp
A1 Hoffmeister, Michael
A1 Hopper, John L
A1 Hsu, Wan-Ling
A1 Huang, Wen-Yi
A1 Hudson, Thomas J
A1 Hunter, David J
A1 Ibañez-Sanz, Gemma
A1 Idos, Gregory E
A1 Ingersoll, Roxann
A1 Jackson, Rebecca D
A1 Jacobs, Eric J
A1 Jenkins, Mark A
A1 Joshi, Amit D
A1 Joshu, Corinne E
A1 Keku, Temitope O
A1 Key, Timothy J
A1 Kim, Hyeong Rok
A1 Kobayashi, Emiko
A1 Kolonel, Laurence N
A1 Kooperberg, Charles
A1 Kühn, Tilman
A1 Küry, Sébastien
A1 Kweon, Sun-Seog
A1 Larsson, Susanna C
A1 Laurie, Cecelia A
A1 Le Marchand, Loic
A1 Leal, Suzanne M
A1 Lee, Soo Chin
A1 Lejbkowicz, Flavio
A1 Lemire, Mathieu
A1 Li, Christopher I
A1 Li, Li
A1 Lieb, Wolfgang
A1 Lin, Yi
A1 Lindblom, Annika
A1 Lindor, Noralane M
A1 Ling, Hua
A1 Louie, Tin L
A1 Männistö, Satu
A1 Markowitz, Sanford D
A1 Martín, Vicente
A1 Masala, Giovanna
A1 McNeil, Caroline E
A1 Melas, Marilena
A1 Milne, Roger L
A1 Moreno, Lorena
A1 Murphy, Neil
A1 Myte, Robin
A1 Naccarati, Alessio
A1 Newcomb, Polly A
A1 Offit, Kenneth
A1 Ogino, Shuji
A1 Onland-Moret, N Charlotte
A1 Pardini, Barbara
A1 Parfrey, Patrick S
A1 Pearlman, Rachel
A1 Perduca, Vittorio
A1 Pharoah, Paul D P
A1 Pinchev, Mila
A1 Platz, Elizabeth A
A1 Prentice, Ross L
A1 Pugh, Elizabeth
A1 Raskin, Leon
A1 Rennert, Gad
A1 Rennert, Hedy S
A1 Riboli, Elio
A1 Rodríguez-Barranco, Miguel
A1 Romm, Jane
A1 Sakoda, Lori C
A1 Schafmayer, Clemens
A1 Schoen, Robert E
A1 Seminara, Daniela
A1 Shah, Mitul
A1 Shelford, Tameka
A1 Shin, Min-Ho
A1 Shulman, Katerina
A1 Sieri, Sabina
A1 Slattery, Martha L
A1 Southey, Melissa C
A1 Stadler, Zsofia K
A1 Stegmaier, Christa
A1 Su, Yu-Ru
A1 Tangen, Catherine M
A1 Thibodeau, Stephen N
A1 Thomas, Duncan C
A1 Thomas, Sushma S
A1 Toland, Amanda E
A1 Trichopoulou, Antonia
A1 Ulrich, Cornelia M
A1 Van Den Berg, David J
A1 van Duijnhoven, Franzel J B
A1 Van Guelpen, Bethany
A1 van Kranen, Henk
A1 Vijai, Joseph
A1 Visvanathan, Kala
A1 Vodicka, Pavel
A1 Vodickova, Ludmila
A1 Vymetalkova, Veronika
A1 Weigl, Korbinian
A1 Weinstein, Stephanie J
A1 White, Emily
A1 Win, Aung Ko
A1 Wolf, C Roland
A1 Wolk, Alicja
A1 Woods, Michael O
A1 Wu, Anna H
A1 Zaidi, Syed H
A1 Zanke, Brent W
A1 Zhang, Qing
A1 Zheng, Wei
A1 Scacheri, Peter C
A1 Potter, John D
A1 Bassik, Michael C
A1 Kundaje, Anshul
A1 Casey, Graham
A1 Moreno, Victor
A1 Abecasis, Goncalo R
A1 Nickerson, Deborah A
A1 Gruber, Stephen B
A1 Hsu, Li
A1 Peters, Ulrike
AB To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide association study data, and tested for association in 34,869 cases and 29,051 controls. Findings were followed up in an additional 23,262 cases and 38,296 controls. We discovered a strongly protective 0.3% frequency variant signal at CHD1. In a combined meta-analysis of 125,478 individuals, we identified 40 new independent signals at P 
YR 2018
FD 2018-12-03
LK http://hdl.handle.net/10668/13276
UL http://hdl.handle.net/10668/13276
LA en
DS RISalud
RD Apr 19, 2025