%0 Journal Article
%A Huyghe, Jeroen R
%A Bien, Stephanie A
%A Harrison, Tabitha A
%A Kang, Hyun Min
%A Chen, Sai
%A Schmit, Stephanie L
%A Conti, David V
%A Qu, Conghui
%A Jeon, Jihyoun
%A Edlund, Christopher K
%A Greenside, Peyton
%A Wainberg, Michael
%A Schumacher, Fredrick R
%A Smith, Joshua D
%A Levine, David M
%A Nelson, Sarah C
%A Sinnott-Armstrong, Nasa A
%A Albanes, Demetrius
%A Alonso, M Henar
%A Anderson, Kristin
%A Arnau-Collell, Coral
%A Arndt, Volker
%A Bamia, Christina
%A Banbury, Barbara L
%A Baron, John A
%A Berndt, Sonja I
%A Bézieau, Stéphane
%A Bishop, D Timothy
%A Boehm, Juergen
%A Boeing, Heiner
%A Brenner, Hermann
%A Brezina, Stefanie
%A Buch, Stephan
%A Buchanan, Daniel D
%A Burnett-Hartman, Andrea
%A Butterbach, Katja
%A Caan, Bette J
%A Campbell, Peter T
%A Carlson, Christopher S
%A Castellví-Bel, Sergi
%A Chan, Andrew T
%A Chang-Claude, Jenny
%A Chanock, Stephen J
%A Chirlaque, Maria-Dolores
%A Cho, Sang Hee
%A Connolly, Charles M
%A Cross, Amanda J
%A Cuk, Katarina
%A Curtis, Keith R
%A de la Chapelle, Albert
%A Doheny, Kimberly F
%A Duggan, David
%A Easton, Douglas F
%A Elias, Sjoerd G
%A Elliott, Faye
%A English, Dallas R
%A Feskens, Edith J M
%A Figueiredo, Jane C
%A Fischer, Rocky
%A FitzGerald, Liesel M
%A Forman, David
%A Gala, Manish
%A Gallinger, Steven
%A Gauderman, W James
%A Giles, Graham G
%A Gillanders, Elizabeth
%A Gong, Jian
%A Goodman, Phyllis J
%A Grady, William M
%A Grove, John S
%A Gsur, Andrea
%A Gunter, Marc J
%A Haile, Robert W
%A Hampe, Jochen
%A Hampel, Heather
%A Harlid, Sophia
%A Hayes, Richard B
%A Hofer, Philipp
%A Hoffmeister, Michael
%A Hopper, John L
%A Hsu, Wan-Ling
%A Huang, Wen-Yi
%A Hudson, Thomas J
%A Hunter, David J
%A Ibañez-Sanz, Gemma
%A Idos, Gregory E
%A Ingersoll, Roxann
%A Jackson, Rebecca D
%A Jacobs, Eric J
%A Jenkins, Mark A
%A Joshi, Amit D
%A Joshu, Corinne E
%A Keku, Temitope O
%A Key, Timothy J
%A Kim, Hyeong Rok
%A Kobayashi, Emiko
%A Kolonel, Laurence N
%A Kooperberg, Charles
%A Kühn, Tilman
%A Küry, Sébastien
%A Kweon, Sun-Seog
%A Larsson, Susanna C
%A Laurie, Cecelia A
%A Le Marchand, Loic
%A Leal, Suzanne M
%A Lee, Soo Chin
%A Lejbkowicz, Flavio
%A Lemire, Mathieu
%A Li, Christopher I
%A Li, Li
%A Lieb, Wolfgang
%A Lin, Yi
%A Lindblom, Annika
%A Lindor, Noralane M
%A Ling, Hua
%A Louie, Tin L
%A Männistö, Satu
%A Markowitz, Sanford D
%A Martín, Vicente
%A Masala, Giovanna
%A McNeil, Caroline E
%A Melas, Marilena
%A Milne, Roger L
%A Moreno, Lorena
%A Murphy, Neil
%A Myte, Robin
%A Naccarati, Alessio
%A Newcomb, Polly A
%A Offit, Kenneth
%A Ogino, Shuji
%A Onland-Moret, N Charlotte
%A Pardini, Barbara
%A Parfrey, Patrick S
%A Pearlman, Rachel
%A Perduca, Vittorio
%A Pharoah, Paul D P
%A Pinchev, Mila
%A Platz, Elizabeth A
%A Prentice, Ross L
%A Pugh, Elizabeth
%A Raskin, Leon
%A Rennert, Gad
%A Rennert, Hedy S
%A Riboli, Elio
%A Rodríguez-Barranco, Miguel
%A Romm, Jane
%A Sakoda, Lori C
%A Schafmayer, Clemens
%A Schoen, Robert E
%A Seminara, Daniela
%A Shah, Mitul
%A Shelford, Tameka
%A Shin, Min-Ho
%A Shulman, Katerina
%A Sieri, Sabina
%A Slattery, Martha L
%A Southey, Melissa C
%A Stadler, Zsofia K
%A Stegmaier, Christa
%A Su, Yu-Ru
%A Tangen, Catherine M
%A Thibodeau, Stephen N
%A Thomas, Duncan C
%A Thomas, Sushma S
%A Toland, Amanda E
%A Trichopoulou, Antonia
%A Ulrich, Cornelia M
%A Van Den Berg, David J
%A van Duijnhoven, Franzel J B
%A Van Guelpen, Bethany
%A van Kranen, Henk
%A Vijai, Joseph
%A Visvanathan, Kala
%A Vodicka, Pavel
%A Vodickova, Ludmila
%A Vymetalkova, Veronika
%A Weigl, Korbinian
%A Weinstein, Stephanie J
%A White, Emily
%A Win, Aung Ko
%A Wolf, C Roland
%A Wolk, Alicja
%A Woods, Michael O
%A Wu, Anna H
%A Zaidi, Syed H
%A Zanke, Brent W
%A Zhang, Qing
%A Zheng, Wei
%A Scacheri, Peter C
%A Potter, John D
%A Bassik, Michael C
%A Kundaje, Anshul
%A Casey, Graham
%A Moreno, Victor
%A Abecasis, Goncalo R
%A Nickerson, Deborah A
%A Gruber, Stephen B
%A Hsu, Li
%A Peters, Ulrike
%T Discovery of common and rare genetic risk variants for colorectal cancer.
%D 2018
%U http://hdl.handle.net/10668/13276
%X To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide association study data, and tested for association in 34,869 cases and 29,051 controls. Findings were followed up in an additional 23,262 cases and 38,296 controls. We discovered a strongly protective 0.3% frequency variant signal at CHD1. In a combined meta-analysis of 125,478 individuals, we identified 40 new independent signals at P 
%~