RT Journal Article
T1 Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study.
A1 Chaparro, Maria
A1 Garre, Ana
A1 Nuñez Ortiz, Andrea
A1 Diz-Lois Palomares, Maria Teresa
A1 Rodriguez, Cristina
A1 Riestra, Sabino
A1 Vela, Milagros
A1 Benitez, Jose Manuel
A1 Fernandez Salgado, Estela
A1 Sanchez Rodriguez, Eugenia
A1 Hernandez, Vicent
A1 Ferreiro-Iglesias, Rocio
A1 Ponferrada Díaz, Angel
A1 Barrio, Jesus
A1 Huguet, Jose Maria
A1 Sicilia, Beatriz
A1 Martin-Arranz, Maria Dolores
A1 Calvet, Xavier
A1 Ginard, Daniel
A1 Alonso-Abreu, Inmaculada
A1 Fernandez-Salazar, Luis
A1 Varela Trastoy, Pilar
A1 Rivero, Montserrat
A1 Vera-Mendoza, Isabel
A1 Vega, Pablo
A1 Navarro, Pablo
A1 Sierra, Monica
A1 Cabriada, Jose Luis
A1 Aguas, Mariam
A1 Vicente, Raquel
A1 Navarro-Llavat, Merce
A1 Echarri, Ana
A1 Gomollon, Fernando
A1 Guerra Del Rio, Elena
A1 Piñero, Concepcion
A1 Casanova, Maria Jose
A1 Spicakova, Katerina
A1 Ortiz de Zarate, Jone
A1 Torrella Cortes, Emilio
A1 Gutierrez, Ana
A1 Alonso-Galan, Horacio
A1 Hernandez-Martinez, Alvaro
A1 Marrero, Jose Miguel
A1 Lorente Poyatos, Rufo
A1 Calafat, Margalida
A1 Marti Romero, Lidia
A1 Robledo, Pilar
A1 Bosch, Orencio
A1 Jimenez, Nuria
A1 Esteve Comas, Maria
A1 Duque, Jose Maria
A1 Fuentes Coronel, Ana Maria
A1 Josefa Sampedro, Manuela
A1 Sese Abizanda, Eva
A1 Herreros Martinez, Belen
A1 Pozzati, Liliana
A1 Fernandez Rosaenz, Hipolito
A1 Crespo Suarez, Belen
A1 Lopez Serrano, Pilar
A1 Lucendo, Alfredo J
A1 Muñoz Vicente, Margarita
A1 Bermejo, Fernando
A1 Ramirez Palanca, Jose Joaquin
A1 Menacho, Margarita
A1 Carmona, Amalia
A1 Camargo, Raquel
A1 Torra Alsina, Sandra
A1 Maroto, Nuria
A1 Nerin de la Puerta, Juan
A1 Castro, Elena
A1 Marin-Jimenez, Ignacio
A1 Botella, Belen
A1 Sapiña, Amparo
A1 Cruz, Noelia
A1 Forcelledo, Jose Luis F
A1 Bouhmidi, Abdel
A1 Castaño-Milla, Carlos
A1 Opio, Veronica
A1 Nicolas, Isabel
A1 Kutz, Marcos
A1 Abraldes Bechiarelli, Alfredo
A1 Gordillo, Jordi
A1 Ber, Yolanda
A1 Torres Dominguez, Yolanda
A1 Novella Duran, Maria Teresa
A1 Rodriguez Mondejar, Silvia
A1 Martinez-Cerezo, Francisco J
A1 Kolle, Lilyan
A1 Sabat, Miriam
A1 Ledezma, Cesar
A1 Iyo, Eduardo
A1 Roncero, Oscar
A1 Irisarri, Rebeca
A1 Lluis, Laia
A1 Blazquez Gomez, Isabel
A1 Zapata, Eva Maria
A1 Jose Alcala, Maria
A1 Martinez Pascual, Cristina
A1 Montealegre, Maria
A1 Mata, Laura
A1 Monrobel, Ana
A1 Hernandez Camba, Alejandro
A1 Hernandez, Luis
A1 Tejada, Maria
A1 Mir, Alberto
A1 Galve, Maria Luisa
A1 Soler, Marta
A1 Hervias, Daniel
A1 Gomez-Valero, Jose Antonio
A1 Barreiro-de Acosta, Manuel
A1 Rodriguez-Artalejo, Fernando
A1 Garcia-Esquinas, Esther
A1 Gisbert, Javier P
K1 Crohn’s disease
K1 Epidemiology
K1 Incidence
K1 Inflammatory bowel disease
K1 Ulcerative colitis
AB Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p< 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery.
PB MDPI
SN 2077-0383
YR 2021
FD 2021-06-15
LK http://hdl.handle.net/10668/18136
UL http://hdl.handle.net/10668/18136
LA en
NO Chaparro M, Garre A, Núñez Ortiz A, Diz-Lois Palomares MT, Rodríguez C, Riestra S, et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J Clin Med. 2021 Jun 29;10(13):2885. doi: 10.3390/jcm10132885. Erratum in: J Clin Med. 2022 Sep 30;11(19):5816
DS RISalud
RD Apr 6, 2025