RT Journal Article
T1 3D DXA Hip Differences in Patients with Acromegaly or Adult Growth Hormone Deficiency.
A1 Gracia-Marco, Luis
A1 Gonzalez-Salvatierra, Sheila
A1 Garcia-Martin, Antonia
A1 Ubago-Guisado, Esther
A1 Garcia-Fontana, Beatriz
A1 Gil-Cosano, José Juan
A1 Muñoz-Torres, Manuel
K1 DXA
K1 bone QCT/microCT
K1 bone modelling and remodelling
K1 osteoporosis
AB The skeleton is regulated by and responds to pituitary hormones, especially when the circulating levels are perturbed in disease. This study aims to analyse the between-group differences in 3D dual-energy X-ray absorptiometry (DXA) parameters at the hip site among patients with acromegaly or adult growth hormone deficiency (AGHD) and a healthy control group. The current cross-sectional study includes data for 67 adults, 20 with acromegaly, 14 with AGHD and 33 healthy controls. We obtained the areal bone mineral density (aBMD) outcomes using DXA and cortical and trabecular parameters using 3D-DXA software (3D-SHAPER). The mean-adjusted 3D-DXA parameters did not differ between acromegaly patients and the controls (p > 0.05); however, we found cortical bone impairment (-7.3% to -8.4%; effect size (ES) = 0.78) in AGHD patients (p  0.05); however, we found cortical bone impairment (-7.3% to -8.4%; effect size (ES) = 0.78) in AGHD patients (p
SN 2077-0383
YR 2021
FD 2021-02-09
LK https://hdl.handle.net/10668/26117
UL https://hdl.handle.net/10668/26117
LA en
DS RISalud
RD Apr 17, 2025